R7882

Acetato de retinil

solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

• Sinónimos: Acetato de retinol, Acetato de vitamina A
• Fórmula empírica (notación de Hill): C₂₂H₃₂O₂
• Número CAS: 127-47-9
• Peso molecular: 328.49
• Beilstein: 1915439
• Número CE: 204-844-2
• Número MDL: MFCD00019413
• Código UNSPSC: 12352205
• eCl@ss: 34058009
• ID de la sustancia en PubChem: 24899401
• NACRES: NA.75

Propiedades

• origen biológico: synthetic
• Nivel de calidad: 200
• Línea del producto: BioReagent
• Ensayo: ≥90% (HPLC)
• Formulario: solid or viscous liquid
• potencia: ~2,800,000 I.U. per g
• mol peso: M_w 328.49 g/mol
• técnicas: cell culture | mammalian: suitable
• color: light yellow to dark yellow
• mp: 57-58 °C
• solubilidad: absolute ethanol: 25 mg/mL (lit.)
• temp. de almacenamiento: −20°C
• cadena SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
• InChI: 1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
• Clave InChI: QGNJRVVDBSJHIZ-QHLGVNSISA-N

Descripción

Descripción general

Retinyl-acetate is a natural and ester derivative of vitamin A.[1] It is found in classical media formulations such as M-199; NCTC-109 and William′s Medium E. Vitamin A is a component of serum useful in most serum containing cell culture systems, which receive some level of vitamin A.

Aplicación

Retinyl acetate has been used as a standard to measure the concentration of vitamin C in high performance liquid chromatography analysis (HPLC)[2] and as a supplement in the preparation of the complete medium.[3]

Acciones bioquímicas o fisiológicas

The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells. Retinyl-acetate is known to be effective in treating breast cancer.[4]

Nota de preparación

The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid.

Otras notas

All trans

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H360D,H413
• Consejos de prudencia: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Aquatic Chronic 4 - Repr. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 2
• Equipo de protección personal: Eyeshields, Gloves, type ABEK (EN14387) respirator filter