If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
D6750
Sodium deoxycholate
≥97% (titration)
Synonym(s):
3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
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description
anionic
Quality Level
Assay
≥97% (titration)
form
powder
mol wt
micellar avg mol wt 1200-5000
aggregation number
3-12
CMC
2-6 mM (20-25°C)
solubility
water: 50 mg/mL, clear, colorless to light yellow
HLB
16
functional group
carboxylic acid
shipped in
ambient
storage temp.
room temp
SMILES string
[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
InChI
1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
InChI key
FHHPUSMSKHSNKW-SMOYURAASA-M
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This Item | 264103 | 1.06504 | S1827 |
|---|---|---|---|
| form powder | form solid | form solid | form powder |
| assay ≥97% (titration) | assay ≥99% (TLC) | assay - | assay ≥98% (HPLC) |
| aggregation number 3-12 | aggregation number 3 - 12, 3-12 | aggregation number - | aggregation number 3-12 |
| storage temp. room temp | storage temp. 15-25°C | storage temp. 15-25°C | storage temp. - |
| HLB 16 | HLB 16 | HLB - | HLB 16 |
| solubility water: 50 mg/mL, clear, colorless to light yellow | solubility - | solubility 330 g/L | solubility - |
General description
Moreover, Sodium Deoxycholate extends its utility to nucleic acid extraction from cells and tissues. By lysing cells and disrupting cellular structures, it facilitates the release and purification of nucleic acids, proving valuable in cell biology and biochemical research. Beyond these applications, its effectiveness in cell lysis processes positions it as a valuable tool for breaking down cells and releasing their contents, finding applications in diverse biological studies, encompassing microscopy, cell biology, and biochemical research.
Application
Biochem/physiol Actions
Features and Benefits
Other Notes
comparable product
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
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This product is intended for research use only and is not suitable for human or veterinary use. While not tested for in vitro or in vivo use, this product has been used successfully in animal models by other customers. Please see the links below to review example publications:
Corroboration of naringin effects on the intestinal absorption and pharmacokinetic behavior of candesartan cilexetil solid dispersions using in-situ rat models.
https://pubmed.ncbi.nlm.nih.gov/24918161/MicroRNA-101 inhibits rat cardiac hypertrophy by targeting Rab1a.
https://pubmed.ncbi.nlm.nih.gov/25850725/A model of metabolic syndrome and related diseases with intestinal endotoxemia in rats fed a high fat and high sucrose diet.
https://pubmed.ncbi.nlm.nih.gov/25502558/Helpful?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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