Skip to Content
Merck

I2393

IL-1β rat

≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(s):

IL-1β, Interleukin-1β from rat, Lymphocyte activating factor

Slide 1 of 1
Sign In to View Organizational & Contract Pricing.

Select a Size

I2393-10UG

€776.00

I2393-50UG

€1,360.00

€776.00

Check Cart for Availability

About This Item

MDL number:
MFCD01094098
UNSPSC Code:
12352202
NACRES:
NA.77

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Interleukin-1β from rat, IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

biological source

rat

Quality Level

100

recombinant

expressed in E. coli

Assay

≥98% (SDS-PAGE and HPLC)

form

lyophilized powder

potency

0.01-0.1 ng/mL ED50/EC50

mol wt

17.3 kDa

packaging

pkg of 10 and 50 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg

UniProt accession no.

Q63264

storage temp.

−20°C

Gene Information

rat ... Il1b(24494)

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
I5271I3901H6291
Interleukin-1&#946; from rat IL-1&#946;, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Sigma-Aldrich

I2393

Interleukin-1β from rat

Interleukin-1&#946; from mouse IL-1&#946;, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Sigma-Aldrich

I5271

Interleukin-1β from mouse

Interleukin-1&#945; from rat IL-1&#945;, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Sigma-Aldrich

I3901

Interleukin-1α from rat

Interleukin-1&#946; human IL-1&#946;, recombinant, expressed in HEK 293 cells, HumanKine&#174;, suitable for cell culture, endotoxin tested

Sigma-Aldrich

H6291

Interleukin-1β human

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in HEK 293 cells

assay

≥98% (SDS-PAGE and HPLC)

assay

≥97% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

biological source

rat

biological source

mouse

biological source

rat

biological source

human

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin-2.1 IL-1 is primarily released from stimulated macrophages and monocytes, but is also released from several other cell types,2 and is thought to play a key role in inflammatory and immune responses.3 Other synonyms for IL-1 include: Endogenous Pyrogen (EP), Mitogenic Protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRFH), B cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF).4 The two closely related agents, Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) bind to the same cell surface receptor, elicit nearly identical biological responses and yet share 25% homology in their amino acid sequence. Recombinant rat IL-1β is a 17.3 kDa protein containing 153 amino acid residues.

Physical form

Lyophilized from a 0.2 μm filtered buffered solution.

Analysis Note

The biological activity is measured in a cell proliferation assay using murine D10S cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCL5731
MKCK4348
MKCJ6930
MKCH7142
MKCG9243

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Wei Zhou et al.
Journal of neurophysiology, 117(6), 2282-2291 (2017-03-17)
Excessive inflammation including IL-1β-initiated signaling is among the earlies reactions that can cause neuronal damage following spinal cord injury (SCI). It has been suggested that microRNAs may participate in stem cell repair to facilitate functional recovery following SCI. In this

Articles

Interleukin Family (IL)

Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.

Related Content

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service