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Merck

L7875

DL-Leucine

≥99% (HPLC)

Synonym(s):

(±)-Amino-4-methylpentanoic acid

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CO2H
CAS Number:
328-39-2
Molecular Weight:
131.17
NACRES:
NA.26
PubChem Substance ID:
24896484
UNSPSC Code:
12352209
EC Number:
206-328-2
MDL number:
MFCD00063087
Beilstein/REAXYS Number:
636005

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Product Name

DL-Leucine, ≥99% (HPLC)

InChI key

ROHFNLRQFUQHCH-UHFFFAOYSA-N

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)

SMILES string

CC(C)CC(N)C(O)=O

assay

≥99% (HPLC)

form

powder

color

white

mp

293-296 °C (subl.) (lit.)

solubility

1 M HCl: soluble

application(s)

detection
peptide synthesis

Quality Level

200

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Show Differences

1 of 4

This Item
855448L800061819
DL-Leucine ≥99% (HPLC)

Sigma-Aldrich

L7875

DL-Leucine

D-Leucine ReagentPlus®, 99%

Sigma-Aldrich

855448

D-Leucine

L-Leucine reagent grade, ≥98% (HPLC)

Sigma-Aldrich

L8000

L-Leucine

L-Leucine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

61819

L-Leucine

form

powder

form

powder (crystals)

form

powder

form

powder or crystals

assay

≥99% (HPLC)

assay

99%

assay

≥98% (HPLC)

assay

≥99.5% (NT)

color

white

color

-

color

white to off-white

color

white

mp

293-296 °C (subl.) (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

solubility

1 M HCl: soluble

solubility

-

solubility

-

solubility

1 M HCl: 0.1 M at 20 °C, clear, colorless

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

Application

DL-Leucine is a racemic mixture of the D- and L- enantiomers of Leucine. DL-Leucine is used to form benzimidazole and pyrimidine hydroxy azo dyes with various transition metals. DL-Leucine may be used for the evaluation of chiral amino acid separation techniques.

DL-Leucine is used for the following applications:
  • Used as a standard for the measurement of free amino acids[1]
  • Used in the process of tritiated leucine uptake[2]
  • Used in solution preparation (various organics were used in different combinations and concentrations to model complex surface tension effects, DL-Leucine is one of them). It is chosen due to its presence in atmospheric aerosols and ice nucleation activity as well as for its surfactant character[3]

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000512645
0000512645
0000489883
0000489883
SLCR4397

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Modeling the surface tension of complex, reactive organic-inorganic mixtures.
A. N. Schwier et al.
Atmospheric Chemistry and Physics, 13, 10721-10732 (2013)
L Sallami et al.
Journal of dairy science, 87(6), 1585-1594 (2004-09-30)
The effect of incorporating a highly autolytic strain (Lactobacillus delbrueckii subsp. bulgaricus UL12) a proteolytic strain (Lactobacillus casei subsp. casei L2A), or a nisin Z-producing strain (Lactococcus lactis, subsp. lactis biovar diacetylactis UL719) into Cheddar cheese starter culture (Lactococcus lactis
H Chang et al.
British journal of haematology, 111(1), 146-156 (2000-11-25)
Transfusion-associated graft-versus-host disease (TA-GVHD) is usually a fatal outcome of blood transfusion therapy, caused by viable leucocytes contained in the donor blood. Most cases of TA-GVHD occur when less than 4-d-old blood is transfused. We therefore examined the molecular changes
Masaki Kajimoto et al.
American journal of physiology. Heart and circulatory physiology, 309(7), H1157-H1165 (2015-08-02)
Nutritional energy support during extracorporeal membrane oxygenation (ECMO) should promote successful myocardial adaptation and eventual weaning from the ECMO circuit. Fatty acids (FAs) are a major myocardial energy source, and medium-chain FAs (MCFAs) are easily taken up by cell and
Satinder K Singh et al.
Nature, 448(7156), 952-956 (2007-08-10)
Sodium-coupled transporters are ubiquitous pumps that harness pre-existing sodium gradients to catalyse the thermodynamically unfavourable uptake of essential nutrients, neurotransmitters and inorganic ions across the lipid bilayer. Dysfunction of these integral membrane proteins has been implicated in glucose/galactose malabsorption, congenital
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