SAB5200108

Anti-SLC14A2 antibody produced in rabbit

Name: Anti-SLC14A2 antibody produced in rabbit
Brand: SIGMA
Price: 435 EUR

1 mg/mL, affinity isolated antibody

Synonym(s):

Anti-Slc14a2, Anti-UT-A1

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100 μG

€435.00

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.43

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

antigen predicted mol wt 127 kDa
antigen predicted mol wt 97 kDa

species reactivity

rat, mouse

concentration

1 mg/mL

technique(s)

immunocytochemistry: suitable
western blot: suitable

NCBI accession no.

NP_062220

UniProt accession no.

Q62668

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Slc14a2(54302)

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Show Differences

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This Item	AV48116	SAB5200104	SAB4503317
Sigma-Aldrich SAB5200108 Anti-SLC14A2 antibody produced in rabbit	Sigma-Aldrich AV48116 Anti-SLC14A1 antibody produced in rabbit	Sigma-Aldrich SAB5200104 Anti-SLC12A3 antibody produced in rabbit	Sigma-Aldrich SAB4503317 Anti-SLC10A7 antibody produced in rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
technique(s) immunocytochemistry: suitable, western blot: suitable	technique(s) immunohistochemistry: suitable, western blot: suitable	technique(s) western blot: suitable	technique(s) ELISA: 1:40000, western blot: 1:500-1:1000
Gene Information rat ... Slc14a2(54302)	Gene Information human ... SLC14A1(6563)	Gene Information human ... SLC12A3(6559) rat ... Slc12a3(54300)	Gene Information human ... SLC10A7(84068)

General description

Solute carrier family 14 member 2 (SLC14A2) is composed of 929 amino acids and is expressed in the collecting duct of the inner medulla in rat kidneys. The gene ID of the protein is 54302.

Immunogen

AA911-929 of the rat sequence

Biochem/physiol Actions

Detects ~97 and 127 kDa.

Solute carrier family 14 member 2 (SLC14A2) plays a crucial role in increasing the permeability of urea in the collecting ducts of the inner medulla in kidneys of rats. It also helps to maintain the concentration of urine.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

PBS, 50% glycerol, and 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

1006

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Functional characterization of the central hydrophilic linker region of the urea transporter UT-A1: cAMP activation and snapin binding.

Abinash C Mistry et al.

American journal of physiology. Cell physiology, 298(6), C1431-C1437 (2010-05-12)

Of the three major protein variants produced by the UT-A gene (UT-A1, UT-A2, and UT-A3) UT-A1 is the largest. It contains UT-A3 as its NH(2)-terminal half and UT-A2 as its COOH-terminal half. When being part of UT-A1, UT-A3 and UT-A2

A mouse model of subacute liver failure with ascites induced by step-wise increased doses of (-)-epigallocatechin-3-gallate.

Xiaoxiao Wang et al.

Scientific reports, 9(1), 18102-18102 (2019-12-04)

Acute liver failure is divided into hyperacute, acute and subacute liver failure. Ascites is a common complication of subacute liver failure. Although animal models of acute liver failure have been established, the study of the pathogenesis of subacute liver failure

Glycoforms of UT-A3 urea transporter with poly-N-acetyllactosamine glycosylation have enhanced transport activity.

Hua Su et al.

American journal of physiology. Renal physiology, 303(2), F201-F208 (2012-04-27)

Urea transporters UT-A1 and UT-A3 are both expressed in the kidney inner medulla. However, the function of UT-A3 remains unclear. Here, we found that UT-A3, which comprises only the NH(2)-terminal half of UT-A1, has a higher urea transport activity than

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