EGFR
epidermal growth factor receptor
Synonymes:
ERBB, ERBB1, HER1, PIG61, mENA
Espèce(s):
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), sheep EGFR (780479), domestic guinea pig Egfr (100725363), dog EGFR (404306), fruit fly Egfr (37455), Horse EGFR (100067755), cow EGFR (407217), naked mole-rat Egfr (101723771) ...Plus
ID UniProtKB:
ID du gène:
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
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ELISA
Numéro du produit
Description
Espèce(s)
Human EGFR / ErbB1 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Espèce(s)
human
Phospho-EGFR (pTyr1068) ELISA Kit, for detection of human phospho-egfr (pTyr1068) in cell and tissue lysates,
Espèce(s)
human
Phospho-EGFR (pSer1070) ELISA Kit, for detection of human, mouse or rat phospho-egfr (pSer1070) in cell and tissue lysates,
Espèce(s)
human
Cell-Based ELISA for detecting phospho-EGFR, in cultured cell lines, 96 assays,
Espèce(s)
human
Phospho-EGFR (pTyr1068) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr1068) and pan-egfr in cell and tissue lysates,
Espèce(s)
human
Small Molecule - Antagonist
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-EGFRvIII Antibody, clone DH8.3, clone DH8.3, from mouse,
Espèces réactives
human
Application
ELISA
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-EGF Receptor antibody, Mouse monoclonal, clone 225, purified from hybridoma cell culture,
Espèces réactives
human
Application
immunoprecipitation (IP)
Anti-EGFR Antibody, neutralizing, clone LA1, clone LA1, Upstate®, from mouse,
Espèces réactives
human
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
neutralization
western blot
immunohistochemistry
immunoprecipitation (IP)
neutralization
western blot
Monoclonal Anti-Epidermal Growth Factor Receptor antibody produced in mouse, clone F4, ascites fluid,
Espèces réactives
human
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Anti-EGFR Antibody, clone LA22, clone LA22, Upstate®, from mouse,
Espèces réactives
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Numéro du produit
Description
Espèce(s)
Gefitinib for system suitability, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Proteins
Numéro du produit
Description
Espèce(s)
Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),
Espèce(s)
human
EGFR Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Espèce(s)
human
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Espèce(s)
human
EGFR (T790M L858R) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Espèce(s)
human
Epidermal Growth Factor Receptor human, buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry),
Espèce(s)
human