72858
2-(2-Methyl-5-nitro-1H-imidazol-1-yl)acetic acid
analytical standard
别名:
1-Carboxymethylmetronidazole, 2-Methyl-5-nitroimidazole-1-acetic acid, Metronidazole-1-acetic acid
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C6H7N3O4
化学文摘社编号:
分子量:
185.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
613770
产品名称
2-(2-Methyl-5-nitro-1H-imidazol-1-yl)acetic acid, analytical standard
InChI
1S/C6H7N3O4/c1-4-7-2-5(9(12)13)8(4)3-6(10)11/h2H,3H2,1H3,(H,10,11)
SMILES string
O=C(O)CN1C(C)=NC=C1[N+]([O-])=O
InChI key
RVEGZXNRNWUYKI-UHFFFAOYSA-N
grade
analytical standard
assay
≥97.5% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
impurities
≤0.5% water
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
B Fredricsson et al.
Gynecologic and obstetric investigation, 24(3), 200-207 (1987-01-01)
Metronidazole kinetics was studied in 5 healthy women after a single dose given intravenously, orally or vaginally, 500, 400 and 500 mg, respectively. Serum levels of the drug and of its hydroxy and acid metabolites were assessed. The results after
E D Ralph et al.
Sexually transmitted diseases, 7(4), 157-160 (1980-10-01)
The susceptibilities of strains of Gardnerella vaginalis (Haemophilus vaginalis), Neisseria gonorrhoeae, and Bacteroides fragilis to metronidazole and its principal oxidative metabolites (1-[2-hydroxyethyl]-2-hydroxymethyl-5-nitroimidazole) ("hydroxy" metabolite) and 1-acetic acid-2-methyl-5-nitroimidazole ("acid" metabolite), were compared by determinations of the minimal inhibitory concentrations (MICs) of
R A Gibson et al.
Clinical chemistry, 30(5), 784-787 (1984-05-01)
Metronidazole and its known metabolites in plasma can be rapidly separated by a "high-pressure" liquid-chromatographic method that can also be adapted for rapid determination of tinidazole. Samples deproteinized with trichloroacetic acid (50 g/L final concentration) undergo isocratic separation on a
D R Guay et al.
Antimicrobial agents and chemotherapy, 25(3), 306-310 (1984-03-01)
The pharmacokinetics of metronidazole, its biologically active alcohol metabolite, and its inactive acid metabolite were studied in five noninfected patients undergoing continuous ambulatory peritoneal dialysis and five patients undergoing hemodialysis. The latter were studied on off-dialysis days as a control
B Salvesen et al.
Scandinavian journal of gastroenterology. Supplement, 91, 31-43 (1984-01-01)
A high-performance liquid chromatography (HPLC) method for the assay of metronidazole and its 2-hydroxymethyl metabolite in sera was compared with a microbiological method, an agar well diffusion technique with Clostridium perfringens as indicator strain. The HPLC technique involves separation of
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持