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Merck

T27502

L-4-Thiazolidinecarboxylic acid

98%

Synonym(s):

L-Thiaproline

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€34.10

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€236.00

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About This Item

Empirical Formula (Hill Notation):
C4H7NO2S
CAS Number:
34592-47-7
Molecular Weight:
133.17
Beilstein:
81065
EC Number:
252-106-3
MDL number:
MFCD00005212
UNSPSC Code:
12352106
PubChem Substance ID:
24900069
NACRES:
NA.22

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Assay

98%

form

powder

optical activity

[α]20/D −141°, c = 1.3 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

color

white

mp

190-200 °C (dec.) (lit.)

SMILES string

OC(=O)[C@@H]1CSCN1

InChI

1S/C4H7NO2S/c6-4(7)3-1-8-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1

InChI key

DZLNHFMRPBPULJ-VKHMYHEASA-N

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This Item
B2129A3506D9628
L-4-Thiazolidinecarboxylic acid 98%

Sigma-Aldrich

T27502

L-4-Thiazolidinecarboxylic acid

L-Aspartic acid β-benzyl ester

Sigma-Aldrich

B2129

L-Aspartic acid β-benzyl ester

L-(−)-Arabitol ≥98% (GC)

Sigma-Aldrich

A3506

L-(−)-Arabitol

3,4-Dihydroxy-L-phenylalanine ≥98% (TLC)

Sigma-Aldrich

D9628

3,4-Dihydroxy-L-phenylalanine

form

powder

form

powder

form

powder

form

powder

assay

98%

assay

≥98%

assay

≥98% (GC)

assay

≥98% (TLC)

color

white

color

white

color

white

color

white to off-white

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

mp

190-200 °C (dec.) (lit.)

mp

225 °C

mp

101-104 °C (lit.)

mp

276-278 °C (lit.)

optical activity

[α]20/D −141°, c = 1.3 in H2O

optical activity

-

optical activity

-

optical activity

-

Application

Used in peptide coupling reactions.[1]

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW8605
MKCV6048
MKCR4193
MKCL3512
MKCG1270

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Bioorganic & Medicinal Chemistry Letters, 4, 887-887 (1994)
Guang-Yong Li et al.
Environmental health perspectives, 115(10), 1460-1466 (2007-10-17)
Formaldehyde (FA) is classified as a human carcinogen and has been linked to increased leukemia rates in some epidemiologic studies. Inhalation of FA induces sensory irritation at relatively low concentrations. However, little is known concerning the cellular alterations observed after
Mónica De la Fuente
The Proceedings of the Nutrition Society, 69(4), 651-659 (2010-09-30)
Several immune functions are markers of health, biological age and predictors of longevity. A chronic oxidative and inflammatory state is the main cause of ageing and the immune system is involved in the rate of ageing. Thus, several murine models
Ana Navarro et al.
Antioxidants & redox signaling, 9(1), 131-141 (2006-11-23)
Male mice on a diet supplemented with thioproline (l-thiazolidine-4-carboxylic acid), a physiological metabolite of 5-hydroxytryptamine, at 2.0 g/kg of food from 28 weeks of age and for their entire life, showed a 23-29% increased median and maximal life span. These
Convergent chemical synthesis of proteins by ligation of peptide hydrazides.
Ge-Min Fang et al.
Angewandte Chemie (International ed. in English), 51(41), 10347-10350 (2012-09-13)
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