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Merck

I0375000

Isoconazole

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole

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About This Item

Empirical Formula (Hill Notation):
C18H14Cl4N2O
CAS Number:
27523-40-6
Molecular Weight:
416.13
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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Product Name

Isoconazole, European Pharmacopoeia (EP) Reference Standard

SMILES string

Clc1c(c(ccc1)Cl)COC(C[n]3cncc3)c2c(cc(cc2)Cl)Cl

InChI

1S/C18H14Cl4N2O/c19-12-4-5-13(17(22)8-12)18(9-24-7-6-23-11-24)25-10-14-15(20)2-1-3-16(14)21/h1-8,11,18H,9-10H2

InChI key

MPIPASJGOJYODL-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

isoconazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Related Categories

Application

Isoconazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Successful therapy of tinea cruris with topical isoconazole in combination with a corticosteroid.
Nahide Onsun et al.
Mycoses, 51 Suppl 4, 27-28 (2008-09-12)
Treatment of candidal intertrigo with a topical combination of isoconazole nitrate and diflucortolone valerate.
Bilal Dogan et al.
Mycoses, 51 Suppl 4, 42-43 (2008-09-12)
Blanka Havlickova et al.
Mycoses, 51 Suppl 4, 16-26 (2008-09-12)
Dermatomycoses are contagious superficial fungal infections, which are highly prevalent in developed and developing countries. Caused by a range of Epidermophyton, Microsporum and Trichophyton species, dermatomycoses manifest on glabrous skin as 'ringworm', an annular scaly lesion with a variable inflammatory
Superficial dermatomycoses worldwide: multinational treatment experience with a combination of isoconazole nitrate and diflucortolone valerate. Introduction.
Viktor A Czaika
Mycoses, 51 Suppl 4, 1-1 (2008-09-12)
Tinea corporis treated with a combined topical therapy containing isoconazole and a corticosteroid.
Jaco Jürgens
Mycoses, 51 Suppl 4, 37-38 (2008-09-12)
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