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Merck

04685

Nε-Methyl-L-lysine hydrochloride

≥98.0% (TLC)

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100 MG

€181.00

500 MG

€676.00

€181.00


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About This Item

Empirical Formula (Hill Notation):
C7H16N2O2 · HCl
CAS Number:
Molecular Weight:
196.68
PubChem Substance ID:
UNSPSC Code:
12352202
NACRES:
NA.32
EC Number:
231-539-1
MDL number:
Assay:
≥98.0% (TLC)

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Product Name

Nε-Methyl-L-lysine hydrochloride, ≥98.0% (TLC)

SMILES string

Cl.CNCCCC[C@H](N)C(O)=O
Cl.CNCCCC[C@H](N)C(O)=O

InChI key

AQELUQTVJOFFBN-RGMNGODLSA-N

InChI

1S/C7H16N2O2.ClH/c1-9-5-3-2-4-6(8)7(10)11;/h6,9H,2-5,8H2,1H3,(H,10,11);1H/t6-;/m0./s1

assay

≥98.0% (TLC)

optical activity

[α]/D 20.5±1.5°, c = 0.1 in 1 M HCl

storage temp.

2-8°C

Quality Level

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1 of 4

This Item
19773737494400-M
assay

≥98.0% (TLC)

assay

≥96% (TLC)

assay

≥95.0% (HPLC)

assay

≥98% dry basis (titration)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

optical activity

[α]/D 20.5±1.5°, c = 0.1 in 1 M HCl

optical activity

[α]/D +11.5±1.0°, c = 1 in H2O

optical activity

-

optical activity

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

10-30°C

Biochem/physiol Actions

N ε-methyl-L-lysine was identified as a lysine analog with inhibitory effects on the growth and sporulation of Penicillium chrysogenum and benzyl-penicillin formation by mycelia. [1]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Methylated lysines and 3-methylhistidine in myosin: tissue and developmental differences.
G Huszar
Methods in enzymology, 106, 287-295 (1984-01-01)
C A Regenstreif et al.
Canadian journal of microbiology, 32(6), 522-524 (1986-06-01)
alpha-Methyl lysine was investigated as a potential inhibitor of lysine transport in Escherichia coli and Bacillus sphaericus. At equimolar concentrations, no inhibition was observed in either organism, but at 10X and 100X the lysine concentration, alpha-methyl lysine caused a 20-50%
Agnes M Móricz et al.
Natural product communications, 6(5), 657-660 (2011-05-28)
The influence of monomethylated basic amino acids [NG-monomethyl-L-arginine (MMA) and Nepsilon-monomethyl-L-lysine (MML)] and ozone capturers (indigo carmine, d-limonene) on the antibacterial effect of the mycotoxins aflatoxins B1, B2, G1 and G2 was studied in BioArena, which is a complex bioautographic
B Maras et al.
European journal of biochemistry, 203(1-2), 81-87 (1992-01-15)
The complete amino acid sequence of glutamate dehydrogenase from the thermoacidophilic archaebacterium Sulfolobus solfataricus has been determined. The sequence was reconstructed by automated sequence analysis of peptides obtained after cleavage by trypsin, cyanogen bromide, Staphylococcus aureus V8 protease and pepsin.
Duy P Nguyen et al.
Journal of the American Chemical Society, 131(40), 14194-14195 (2009-09-24)
Lysine methylation is an important post-translational modification of histone proteins that defines epigenetic status and controls heterochromatin formation, X-chromosome inactivation, genome imprinting, DNA repair, and transcriptional regulation. Despite considerable efforts by chemical biologists to synthesize modified histones for use in

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