63559

D-Mannitol

BioUltra, ≥99.0% (sum of enantiomers, HPLC)

• Synonym(s): Mannite
• Empirical Formula (Hill Notation): C₆H₁₄O₆
• CAS Number: 69-65-8
• Molecular Weight: 182.17
• UNSPSC Code: 12352201
• NACRES: NA.25
• PubChem Substance ID: 57651947
• EC Number: 200-711-8
• Beilstein/REAXYS Number: 1721898
• MDL number: MFCD00064287

Properties

• Product Name: D-Mannitol, BioUltra, ≥99.0% (sum of enantiomers, HPLC)
• InChI key: FBPFZTCFMRRESA-KVTDHHQDSA-N
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
• SMILES string: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• product line: BioUltra
• assay: ≥99.0% (sum of enantiomers, HPLC)
• form: powder
• optical activity: [α]20/D +24.0±1° in borax solution acc. to Ph Eur
• impurities: insoluble matter, passes filter test; reducing sugars, complies; ≤0.0072% free acid (as CH₃COOH)
• ign. residue: ≤0.01% (as SO₄)
• loss: ≤0.05% loss on drying, 20 °C (HV)
• color: white
• pH: 5.0-6.5 (25 °C, 1 M in H₂O)
• mp: 166-168 °C; 167-170 °C (lit.)
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤1 mg/kg; Pb: ≤1 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• UV absorption: λ: 260 nm A_max: 0.04; λ: 280 nm A_max: 0.04
• Quality Level: 200

Description

Application

D-Mannitol is used as an osmolyte and transport facilitator in a variety of biological in vivo and in vitro applications, such as improvement of blood-brain barrier transport and hyperosmolar therapy. D-Mannitol is used as a substrate to identify, differentiate and characterized enzymes such as mannitol dehydrogenase(s). D-Mannitol is used in identify mannitol metabolizing bacteria.

Biochem/physiol Actions

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Used in discontinuous gradient centrifugation for purification of plant protoplasts[1]. Plasmolyticum that reversibly inhibits phenylalanine ammonia-lyase activity of protoplasts at concentrations exceeding 50 mM[2]. Component of the liquid stationary phase in the GLC separation of nitroxylene and xylenol isomers[3].

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)