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Merck

D3689

(S)-3,5-Dihydroxyphenylglycine hydrate

≥98% (HPLC), group I metabotropic glutamate receptor agonist, powder

Synonym(s):

S-DHPG

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€261.00

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€496.00

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About This Item

Empirical Formula (Hill Notation):
C8H9NO4 · xH2O
CAS Number:
162870-29-3
Molecular Weight:
183.16 (anhydrous basis)
MDL number:
MFCD11044457
UNSPSC Code:
12352209
PubChem Substance ID:
24278366
NACRES:
NA.77

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Product Name

(S)-3,5-Dihydroxyphenylglycine hydrate, ≥98% (HPLC), powder

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated
protect from light

color

white

storage temp.

−20°C

SMILES string

O.N[C@H](C(O)=O)c1cc(O)cc(O)c1

InChI

1S/C8H9NO4.H2O/c9-7(8(12)13)4-1-5(10)3-6(11)2-4;/h1-3,7,10-11H,9H2,(H,12,13);1H2/t7-;/m0./s1

InChI key

QZEFIWWBQUKNFA-FJXQXJEOSA-N

Gene Information

human ... GRM1(2911)

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(S)-3,5-Dihydroxyphenylglycine hydrate ≥98% (HPLC), powder

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

SML2177

S 38093-2

form

powder

form

solid

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

-

storage temp.

room temp

storage temp.

2-8°C

storage condition

desiccated, protect from light

storage condition

protect from light

storage condition

desiccated, protect from light

storage condition

desiccated

color

white

color

white

color

-

color

white to beige

Application

(S)-3,5-Dihydroxyphenylglycine hydrate has been used:
  • as mGluR1/5 agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations[1]
  • in ACSF for DHPG stimulation[2]
  • to inject into basolateral amygdala to study its effect on memory expression[3]

Biochem/physiol Actions

(S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

air sensitive

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000217656
0000217656
0000144852
0000124797
0000124796

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