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Merck

H4663

HMBA

≥98% (HPLC), solid

Synonym(s):

10-[(3-Hydroxy-4-methoxybenzylidene)]-9(10H)-anthracenone

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10 MG

€118.00

€118.00

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About This Item

Empirical Formula (Hill Notation):
C22H16O3
CAS Number:
564468-51-5
Molecular Weight:
328.36
NACRES:
NA.77
PubChem Substance ID:
24724500
UNSPSC Code:
12352200
MDL number:
MFCD06411568

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Product Name

HMBA, ≥98% (HPLC), solid

InChI

1S/C22H16O3/c1-25-21-11-10-14(13-20(21)23)12-19-15-6-2-4-8-17(15)22(24)18-9-5-3-7-16(18)19/h2-13,23H,1H3

SMILES string

COc1ccc(cc1O)\C=C2\c3ccccc3C(=O)c4ccccc24

InChI key

MQLACMBJVPINKE-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

solid

solubility

DMSO: soluble 34 mg/mL

storage temp.

−20°C

Quality Level

100

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SML2937X2254T7040
HMBA ≥98% (HPLC), solid

Sigma-Aldrich

H4663

HMBA

iHAP1 ≥98% (HPLC)

Sigma-Aldrich

SML2937

iHAP1

XE-991 ≥98% (HPLC)

Sigma-Aldrich

X2254

XE-991

Tyrphostin 1 ≥98%

Sigma-Aldrich

T7040

Tyrphostin 1

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98%

form

solid

form

powder

form

-

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: soluble 34 mg/mL

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: >20 mg/mL

solubility

chloroform: soluble 50 mg/mL, clear, light yellow, DMSO: soluble

Biochem/physiol Actions

HMBA is an Inhibitor of microtubule polymerization; apoptosis inducer.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
054K4614

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Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP.
Olson, et al.
Molecular Cell, 82, 1708-1723 (2023)
Erwan Dupuis et al.
Talanta, 219, 121345-121345 (2020-09-06)
Capillary electrophoresis (CE) was hyphenated to multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS) to determine the model age of a highly enriched uranium (HEU) sample using the 234U/230Th radiochronometer. The use of hydroxymethylbutyric acid (HMBA) as the CE electrolyte was
Yan Wang et al.
Pharmaceutical research, 31(12), 3538-3548 (2014-06-20)
To determine the effect of PEG modification on pharmacologic and gene delivery properties of polymeric CXCR4 antagonist based on Plerixafor. Polymeric Plerixafor (PAMD) was synthesized from Plerixafor (AMD3100) and grafted with different amounts of PEG (2 kDa). CXCR4 antagonism of the
Seung Han Son et al.
International journal of molecular sciences, 23(12) (2022-06-25)
CP2c, also known as TFCP2, α-CP2, LSF, and LBP-1c, is a prototypic member of the transcription factor (TF) CP2 subfamily involved in diverse ubiquitous and tissue/stage-specific cellular processes and in human malignancies including cancer. Despite its importance, many fundamental regulatory
Dong-Hui Xu et al.
International journal of oncology, 45(1), 264-272 (2014-05-03)
Nucleophosmin (NPM, also known as B23), mainly localized in the nucleolus, has been reported to be overexpressed in many types of human cancer, including colon, ovarian, prostate and gastric cancer. NPM was identified while screening the differential nuclear matrix proteins
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