Skip to Content
Merck

50649

Glyoxal solution

BioReagent, ~40% in H2O (~8.8 M), Molecular Biology

Synonym(s):

Ethanedial, Oxalaldehyde

Slide 1 of 1
Sign In to View Organizational & Contract Pricing.

Select a Size

25 ML

₪552.00

100 ML

₪1,609.00

₪552.00

Please contact Customer Service for Availability
Request a Bulk Order

About This Item

Linear Formula:
OHCCHO
CAS Number:
107-22-2
Molecular Weight:
58.04
UNSPSC Code:
12352114
NACRES:
NA.52
PubChem Substance ID:
57651264
MDL number:
MFCD00006957
Beilstein/REAXYS Number:
1732463

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Glyoxal solution, BioReagent, ~40% in H2O (~8.8 M), Molecular Biology

InChI

1S/C2H2O2/c3-1-2-4/h1-2H

SMILES string

[H]C(=O)C([H])=O

InChI key

LEQAOMBKQFMDFZ-UHFFFAOYSA-N

grade

Molecular Biology

product line

BioReagent

form

liquid

concentration

~40% in H2O (~8.8 M)

impurities

DNases, none detected
 RNases, none detected
 phosphatases, none detected
 proteases, none detected

refractive index

n20/D 1.409

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Ca: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤300 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

storage temp.

2-8°C

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
128465537060N1531
Glyoxal solution BioReagent, ~40% in H2O (~8.8 M), Molecular Biology

Sigma-Aldrich

50649

Glyoxal solution

Glyoxal solution 40 wt. % in H2O

Sigma-Aldrich

128465

Glyoxal solution

Propidium Iodide Solution A convenient form of propidium iodide useful for flow cytometry studies.

Sigma-Aldrich

537060

Propidium Iodide Solution

Denaturation Solution for Northern and Southern blotting

Sigma-Aldrich

N1531

Denaturation Solution

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

room temp

refractive index

n20/D 1.409

refractive index

n20/D 1.4087

refractive index

-

refractive index

-

form

liquid

form

liquid

form

liquid

form

solution

grade

for molecular biology

grade

-

grade

-

grade

for molecular biology

product line

BioReagent

product line

-

product line

-

product line

-

Application

Suitable for
  • nucleic acid denaturation
  • binding of DNA/RNA to nitrocellulose membrane

Biochem/physiol Actions

Glyoxal forms stable complex with guanine residues that results in denaturation of nucleic acids.

Disclaimer

May precipitate on storage; redissolve at 50-60 °C.

General description

Glyoxal is a nucleic acid denaturant. It acts as a specific probe for homopurine strands of DNA.

Other Notes

May precipitate on storage; redissolve at 50-60 °C.
This form of glyoxal is composed of 3 moles of glyoxal and 2 moles of water in a relatively stable configuration.

related product

Product No.
Description
Pricing

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCBL7249V
394949/1
367628/1
354841/1
70586/1

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

R N Skopp et al.
Analytical biochemistry, 169(1), 132-137 (1988-02-15)
This paper describes agarose gel electrophoresis and silver staining of denatured RNAs. Glyoxal- or formaldehyde-denatured RNAs are electrophoresed in an agarose gel cast on a plastic support using an inert, low conductivity buffer. Following electrophoresis, the gel is stained with
Hybridization of denatured RNA transferred or dotted nitrocellulose paper.
P S Thomas
Methods in enzymology, 100, 255-266 (1983-01-01)
M Vojtisková et al.
Journal of biomolecular structure & dynamics, 5(2), 283-296 (1987-10-01)
Plasmid pEJ4, which is a derivative of pUC19 containing an insert with 60-bp-long homopurine.homopyrimidine tract from sea urchin P. miliaris histone gene spacer, was studied by chemical probes of the DNA structure osmium tetroxide and glyoxal. The former probe reacts
Prasanna Channathodiyil et al.
PloS one, 16(1), e0240769-e0240769 (2021-01-23)
A simple method for extraction of high quality RNA from cells that have been fixed, stained and sorted by flow cytometry would allow routine transcriptome analysis of highly purified cell populations and single cells. However, formaldehyde fixation impairs RNA extraction
Catherine Lambert et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 18(1), 59-69 (2012-10-30)
The molecular basis of Alzheimer's disease has not been clearly established, but disruption of brain metal ion homeostasis, particularly copper and zinc, might be closely involved in the pathogenesis of this disease and its characteristic β-amyloid neuropathological features. The use
View All Related Papers

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is this glyoxal deionized?

    1 answer

    1. This glyoxal is not deionized. As mentioned in the DESCRIPTION section under 'Other Notes', the form of glyoxal is composed of 3 moles of glyoxal and 2 moles of water in a relatively stable configuration.

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service