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Merck

61819

L-Leucine

≥99.5% (NT), suitable for NMR, BioUltra

Synonym(s):

(S)-2-Amino-4-methylpentanoic acid

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25 G

₪418.00

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₪1,385.00

₪418.00


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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-522-0
MDL number:
Beilstein/REAXYS Number:
1721722

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Product Name

L-Leucine, BioUltra, ≥99.5% (NT)

InChI key

ROHFNLRQFUQHCH-YFKPBYRVSA-N

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1

SMILES string

CC(C)C[C@H](N)C(O)=O

product line

BioUltra

assay

≥99.5% (NT)

form

powder or crystals

optical activity

[α]20/D +15.5±0.5°, c = 5% in 5 M HCl

technique(s)

NMR: suitable

impurities

insoluble matter, passes filter test
≤0.3% foreign amino acids

ign. residue

≤0.1%

loss

≤0.1% loss on drying, 20 °C (HV)

color

white

mp

>300 °C (lit.)

solubility

1 M HCl: 0.1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤100 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.1 M in 1 M HCl

UV absorption

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05

Quality Level

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1 of 4

This Item
76526W3297031357001
form

powder or crystals

form

-

form

-

form

-

assay

≥99.5% (NT)

assay

-

assay

99%

assay

-

technique(s)

NMR: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

product line

BioUltra

product line

TraceCERT®

product line

-

product line

-

cation traces

Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤100 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg, As: ≤0.1 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Bi: ≤5 mg/kg, Li: ≤5 mg/kg, Sr: ≤5 mg/kg, Cr: ≤5 mg/kg, NH4+: ≤100 mg/kg

cation traces

-

cation traces

-

cation traces

-

color

white

color

white

color

-

color

-

Other Notes

As spacer in isotachophoresis of serum proteins[1][2]; Growth requirement of various microorganisms[3]

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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T. Yagi et al. et al.
Electrophoresis ?83, 503-503 (1984)
T. Hine
Electrophoresis ?83, 541-541 null
CRC Handbook of Microbiology, 4, 1-1 (1974)
Youwen Qiu et al.
Journal of agricultural and food chemistry, 67(32), 8884-8895 (2019-07-28)
Leucine is an essential amino acid in the milk production of bovine mammary glands, but the regulatory roles and molecular mechanisms of leucine are still not known well. This study investigated the roles of leucine on milk synthesis and explored
Gaetano Santulli et al.
The Journal of clinical investigation, 125(5), 1968-1978 (2015-04-07)
The type 2 ryanodine receptor (RyR2) is a Ca2+ release channel on the endoplasmic reticulum (ER) of several types of cells, including cardiomyocytes and pancreatic β cells. In cardiomyocytes, RyR2-dependent Ca2+ release is critical for excitation-contraction coupling; however, a functional

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