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Merck

H1252

Homovanillic acid

>99% purity (TLC), powder

Synonym(s):

4-Hydroxy-3-methoxyphenylacetic acid, HVA

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100 MG

₪133.00

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₪262.00

1 G

₪651.00

₪133.00


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About This Item

Linear Formula:
HOC6H3(OCH3)CH2CO2H
CAS Number:
Molecular Weight:
182.17
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
206-176-7
MDL number:
Beilstein/REAXYS Number:
2213447

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Product Name

Homovanillic acid, Fluorimetric reagent

assay

>99% (TLC)

form

powder

InChI key

QRMZSPFSDQBLIX-UHFFFAOYSA-N

InChI

1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)

SMILES string

COc1cc(CC(O)=O)ccc1O

technique(s)

titration: suitable

color

white to off-white

mp

142-145 °C (lit.)

solubility

ethanol: 50 mg/mL, colorless to light yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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This Item
37133569673C9008
technique(s)

titration: suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

titration: suitable

color

white to off-white

color

-

color

-

color

white to yellow

form

powder

form

powder, crystals or chunks

form

-

form

powder

solubility

ethanol: 50 mg/mL, colorless to light yellow

solubility

-

solubility

-

solubility

ethanol: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

pharmaceutical

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

storage temp.

room temp

storage temp.

-

storage temp.

room temp

Application

Homovanillic acid has been used as a standard in HPLC analysis.[1][2]

Biochem/physiol Actions

Metabolite of dihydroxyphenylacetic acid (DOPAC) by catechol O-methyltransferase; reagent for the fluorimetric determination of glucose oxidase and other oxidative enzymes.[3][4]

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Tashjian AH and Armstrong EJ
Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy (2011)
Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease.
Tillerson JL
Neuroscience, 119, 899-899 (2003)
Practical Fluorescence (1990)
Forced nonuse in unilateral parkinsonian rats exacerbates injury.
Tillerson JL
The Journal of Neuroscience, 22, 6790-6790 (2002)
S J Kish et al.
Journal of neurochemistry, 58(2), 642-648 (1992-02-01)
To examine the possible causal contribution of normal or accelerated aging to the neurodegenerative process of Parkinson's disease, we measured the influence of aging on subregional striatal dopamine and homovanillic acid levels in postmortem brain of 23 neurologically and psychiatrically

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