This product contains Pancreatin and Lactose. The other ingredients and concentrations are considered proprietary.
P1625
Pancreatin from porcine pancreas
≥3 × USP specifications
Synonym(s):
Pancreatin from hog pancreas
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biological source
Porcine pancreas
Quality Level
Agency
USP (specifications)
form
powder
specific activity
≥3 × USP specifications
storage temp.
−20°C
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Related Categories
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This Item | P7545 | P3292 | 1494079 |
|---|---|---|---|
| specific activity ≥3 × USP specifications | specific activity 8 × USP specifications | specific activity 4 × USP specifications | specific activity - |
| biological source Porcine pancreas | biological source - | biological source Porcine pancreas | biological source - |
| form powder | form powder | form powder | form - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. - |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level - |
| agency USP (specifications) | agency - | agency USP (specifications) | agency - |
Application
Pancreatin from porcine pancreas is suitable:
- in a study to assess the treatment of steatorrhea by lipase supplementation therapy[1]
- in a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis[2]
- to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity.[3]
- to assess cleavage by digestive enzymes. It is used for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors[4]
- along with amyloglucosidase for the in vitro digestion of starch in food samples[5]
Biochem/physiol Actions
Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 1
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R Raghunathan et al.
Food chemistry, 221, 1514-1521 (2016-12-17)
The objective of this study was to determine the molecular structure and properties of recently released cultivars of field peas [CDC Golden (CDCG), Abarth (ABAR), CDC Patrick (CDCP) and CDC Amarillo (CDCA)] grown at different locations in Saskatchewan, Canada. Starch
Peter Layer et al.
Pancreas, 26(1), 1-7 (2002-12-25)
Treatment of steatorrhea by lipase supplementation therapy has become more successful in the last decade due to better understanding of the physiology and pathophysiology of the digestive process. Porcine lipase has been the therapeutic standard for several decades and will
Sai Kranthi Vanga et al.
Food research international (Ottawa, Ont.), 137, 109523-109523 (2020-11-26)
In recent years, almond has been considered as one of the most common alternative plant-based protein sources due to its nutritional attributes and health benefits. However, almond protein has a lower digestibility compared with the animal protein. The objective of
Anne R Ryan et al.
Developmental biology, 477, 98-116 (2021-05-18)
Chronic kidney disease (CKD) and end stage renal disease (ESRD) are increasingly frequent and devastating conditions that have driven a surge in the need for kidney transplantation. A stark shortage of organs has fueled interest in generating viable replacement tissues
Hakan Nazlı et al.
Pharmaceuticals (Basel, Switzerland), 14(11) (2021-11-28)
Aprepitant (APR) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its low aqueous solubility. The objective of the current work is to develop self-nanoemulsifying drug delivery systems (SNEDDS) of APR to enhance its aqueous solubility. Preformulation
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Does this product indeed NOT contain lactose or sucrose as extender? I'm asking because the 4x and 8x USP pancreatin products do contain that, but for this 3x USP product it is not mentioned, and I would like to be sure it is not in there.
1 answer-
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what is the shelf life for this item? how long this item can be used after opening
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This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.
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