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Merck

T4071

L-Threonine

Synonym(s):

(2S,3R)-2-Amino-3-hydroxybutyric acid

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About This Item

Linear Formula:
CH3CH(OH)CH(NH2)CO2H
CAS Number:
72-19-5
Molecular Weight:
119.12
EC Number:
200-774-1
UNSPSC Code:
12352209
NACRES:
NA.26
Beilstein/REAXYS Number:
1721646
MDL number:
MFCD00064270

Key Documents

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InChI key

AYFVYJQAPQTCCC-GBXIJSLDSA-N

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

SMILES string

C[C@@H](O)[C@H](N)C(O)=O

biological source

non-animal source

assay

≥98.5%

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested

mp

256 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

suitability

suitable for manufacturing use

foreign activity

cytotoxicity, tested

Quality Level

400

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1 of 4

This Item
61506PHR1242T8441
L-Threonine

SAFC

T4071

L-Threonine

L-Threonine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

61506

L-Threonine

L-Threonine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1242

L-Threonine

L-Threonine from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Sigma-Aldrich

T8441

L-Threonine

biological source

non-animal source

biological source

-

biological source

-

biological source

non-animal source

form

crystalline powder

form

-

form

-

form

powder

assay

≥98.5%

assay

-

assay

-

assay

99.0-101.0%

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested

impurities

-

impurities

-

impurities

endotoxin, tested

suitability

suitable for manufacturing use

suitability

-

suitability

-

suitability

-

foreign activity

cytotoxicity, tested

foreign activity

-

foreign activity

-

foreign activity

-

Application

L-Threonine is a β-hydroxy-α-amino acid. It is an essential amino acid and can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
CDBG8841
CDBG8842
CDBG8569
CDBG8523
CDBG8283

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Journal of leukocyte biology, 98(1), 5-14 (2015-02-04)
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