Merck
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890890P

Avanti

18:1 TAP (DOTAP)

Avanti Polar Lipids

Synonym(s):
1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)
Empirical Formula (Hill Notation):
C42H80NO4Cl
CAS Number:
Molecular Weight:
698.54
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 g (890890P-1g)
pkg of 2 × 100 mg (890890P-200mg)
pkg of 5 × 100 mg (890890P-500mg)
pkg of 1 × 25 mg (890890P-25mg)

manufacturer/tradename

Avanti Polar Lipids

application(s)

advanced drug delivery

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Cl-]

InChI

1S/C42H80NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,40H,6-19,24-39H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;

InChI key

KSXTUUUQYQYKCR-LQDDAWAPSA-M

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18:1 TAP (DOTAP) Avanti Polar Lipids

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14:0 PE-DTPA

form

powder

form

powder

form

powder

form

powder

packaging

pkg of 1 × 1 g (890890P-1g), pkg of 2 × 100 mg (890890P-200mg), pkg of 5 × 100 mg (890890P-500mg), pkg of 1 × 25 mg (890890P-25mg)

packaging

pkg of 1 × 5 mg (791300P-5mg)

packaging

pkg of 1 × 5 mg (790106P-5mg)

packaging

pkg of 1 × 5 mg (790535P-5mg)

manufacturer/tradename

Avanti Polar Lipids

manufacturer/tradename

Avanti Polar Lipids 791300P

manufacturer/tradename

Avanti Polar Lipids 790106P

manufacturer/tradename

Avanti Polar Lipids 790535P

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

application(s)

advanced drug delivery

application(s)

-

application(s)

-

application(s)

advanced drug delivery

Application

18:1 TAP (DOTAP) has been used in chloroform solutions to form dry film in the preparation of cationic liposomes. It has also been used in standard stock solution used for the preparation of cationic liposomes.

Biochem/physiol Actions

DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP. DOTAP mediates gene knockdown technique in hematopoietic stem cells (HSCs).

Packaging

5 mL Clear Glass Sealed Ampule (890890P-200mg)
5 mL Clear Glass Sealed Ampule (890890P-25mg)
5 mL Clear Glass Sealed Ampule (890890P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (890890P-1g)

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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