Merck
All Photos(2)

Documents

Safety Information

1.07478

SAFC

1,2-Propanediol

EMPROVE® EXPERT, Ph. Eur., BP, USP

Sign Into View Organizational & Contract Pricing

Synonym(s):
1,2-Propanediol, 1,2-Propylene glycol
Linear Formula:
CH3CH(OH)CH2OH
CAS Number:
Molecular Weight:
76.09
MDL number:
EC Index Number:
200-338-0

Agency

BP
Ph. Eur.
USP

Quality Level

vapor pressure

0.11 hPa ( 20 °C)

product line

EMPROVE® EXPERT

Assay

≥99.5% (GC)

form

liquid

autoignition temp.

371 °C

expl. lim.

2.4-17.4 % (v/v)

refractive index

n20/D 1.43

pH

6-8 (20 °C, 100 g/L in H2O)

bp

188 °C/1013 hPa

mp

-59 °C

transition temp

flash point 99 °C

density

1.04 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
parenterals
parenterals
pharmaceutical
semi-solid formulation

storage temp.

2-30°C

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
8228116033134368
1,2-Propanediol EMPROVE® EXPERT, Ph. Eur., BP, USP

1.07478

1,2-Propanediol

1,2-Propanediol tested according to Ph. Eur.

82281

1,2-Propanediol

1,2-Propanediol meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

16033

1,2-Propanediol

1,2-Propanediol ReagentPlus®, 99%

134368

1,2-Propanediol

assay

≥99.5% (GC)

assay

-

assay

≥99.5%

assay

99%

application(s)

liquid formulation
ophthalmics
parenterals
parenterals
pharmaceutical
semi-solid formulation

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

form

liquid

form

viscous liquid

form

liquid

form

liquid

transition temp

flash point 99 °C

transition temp

-

transition temp

-

transition temp

-

mp

-59 °C

mp

−60 °C (lit.)

mp

−60 °C (lit.)

mp

−60 °C (lit.)

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propylene glycol is used as solvent in a variety of liquid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

219.2 °F - closed cup

Flash Point(C)

104 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Flammable liquids
Type 3 petroleums
Hazardous rank III
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 6

1 of 6

Propylene glycol ≥99.5% (GC), FCC, FG

Sigma-Aldrich

W294004

Propylene glycol

Ethanolamine EMPROVE® EXPERT, Ph. Eur., BP, NF

SAFC

1.37044

Ethanolamine

Propylene glycol British Pharmacopoeia (BP) Reference Standard

BP868

Propylene glycol

Benzoic acid powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, E 210

SAFC

1.00130

Benzoic acid

Glycerol tested according to Ph. Eur., anhydrous

Sigma-Aldrich

49779

Glycerol

Propylene glycol Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1051

Propylene glycol

Articles

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

Related Content

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service