MAB2040

Anti-Heparin/Heparan Sulfate Antibody, clone T320.11

Name: Anti-Heparin/Heparan Sulfate Antibody, clone T320.11
Brand: MM

clone T320.11, Chemicon^®, from mouse

Synonym(s):

Anti-Heparan Sulfate, Clone T320.11 Anti-Heparin, Heparan Sulfate Detection

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This item can only be ordered on the Merck Millipore website.

About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Key Documents

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biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

T320.11, monoclonal

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon^®

technique(s)

ELISA: suitable
radioimmunoassay: suitable
western blot: suitable

isotype

IgG1

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... HSPG2(3339)

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This Item	SAB4301218	MAB1948P	MAB463
Sigma-Aldrich MAB2040 Anti-Heparin/Heparan Sulfate Antibody, clone T320.11	Sigma-Aldrich SAB4301218 Anti-HSPG2 antibody produced in rabbit	Sigma-Aldrich MAB1948P Anti-Heparan Sulfate Proteoglycan (Perlecan) Antibody, clone A7L6	Sigma-Aldrich MAB463 Anti-Estrogen Receptor Antibody, clone B10
antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form purified antibody	antibody form ascites fluid
biological source mouse	biological source rabbit	biological source rat	biological source mouse
clone T320.11, monoclonal	clone polyclonal	clone A7L6, monoclonal	clone B10, monoclonal
Gene Information human ... HSPG2(3339)	Gene Information human ... HSPG2(3339)	Gene Information human ... HSPG2(3339)	Gene Information human ... HSPG2(3339)
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in wet ice

General description

64 kDa

Application

Detect Heparin/Heparan Sulfate using this Anti-Heparin/Heparan Sulfate Antibody, clone T320.11 validated for use in ELISA, RIA & WB.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

Western blotting (recognizes heparan sulfate proteoglycan) 1:1000

EIA/RIA: Suggested concentration 1-10 μg/mL.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with heparin/heparan sulfate. Low affinity cross-reactivity with DNA. It is reported that clone also cross reacts with dextran sulfate (Mahmood, 2002).

Physical form

Format: Purified

Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.

Preparation Note

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Widely expressed

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB2040:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Oocyte Cytoplasmic Gas6 and Heparan Sulfate (HS) are Required to Establish the Open Chromatin State in Nuclei During Remodeling and Reprogramming.

Kyeoung-Hwa Kim et al.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 45(1), 37-53 (2018-01-10)

Previously, we found that silencing of growth arrest-specific gene 6 (Gas6) in oocytes impaired cytoplasmic maturation, resulting in failure of sperm chromatin decondensation (SCD) and pronuclear (PN) formation after fertilization. Thus, we conducted this study to determine the effect of

Investigation of the invasion mechanism mediated by the outer membrane protein PagN of Salmonella Typhimurium.

Emilie Barilleau et al.

BMC microbiology, 21(1), 153-153 (2021-05-23)

Salmonella can invade host cells via a type three secretion system called T3SS-1 and its outer membrane proteins, PagN and Rck. However, the mechanism of PagN-dependent invasion pathway used by Salmonella enterica, subspecies enterica serovar Typhimurium remains unclear. Here, we

UDP-N-acetylglucosamine transporter (SLC35A3) regulates biosynthesis of highly branched N-glycans and keratan sulfate.

Maszczak-Seneczko, D; Sosicka, P; Olczak, T; Jakimowicz, P; Majkowski, M; Olczak, M

The Journal of Biological Chemistry null

Enhancing gene delivery of adeno-associated viruses by cell-permeable peptides.

Liu, Y; Kim, YJ; Ji, M; Fang, J; Siriwon, N; Zhang, LI; Wang, P

Molecular therapy. Methods & clinical development null

A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells.

Thomas Welte et al.

iScience, 24(11), 103349-103349 (2021-11-27)

Myeloid-derived suppressor cells (MDSCs) infiltrate cancer tissue, promote tumor growth, and are associated with resistance to cancer therapies. However, there is no practical approach available to distinguish MDSCs from mature counterparts inside tumors. Here, we show that a recently isolated

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