D7008

Dihydroethidium

Name: Dihydroethidium
Brand: SIAL
Price: 21070 JPY

≥95% purity, powder

Synonym(s):

2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenanthridine, 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine, Hydroethidine

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10 MG

¥21,070

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₂₁N₃

CAS Number:

104821-25-2

Molecular Weight:

315.41

Beilstein:

5107482

MDL number:

MFCD00077335

UNSPSC Code:

12171500

PubChem Substance ID:

24894069

NACRES:

NA.47

Key Documents

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Product Name

Dihydroethidium, ≥95%

Quality Level

100

Assay

≥95%

form

powder

technique(s)

titration: suitable

color

pink to very dark red

solubility

chloroform: 20 mg/mL

fluorescence

λ_ex 370 nm; λ_em 420 nm (for cytoplasm of living cells)
λ_ex 535 nm; λ_em 610 nm (for chromatin of living cells)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

CCN1C(c2ccccc2)c3cc(N)ccc3-c4ccc(N)cc14

InChI

1S/C21H21N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,21H,2,22-23H2,1H3

InChI key

XYJODUBPWNZLML-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item	37291	D4784	A8251
Sigma-Aldrich D7008 Dihydroethidium	Sigma-Aldrich 37291 Dihydroethidium	Sigma-Aldrich D4784 4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride	Sigma-Aldrich A8251 Acriflavine hydrochloride
technique(s) titration: suitable	technique(s) -	technique(s) titration: suitable	technique(s) microbe id \| staining: suitable
fluorescence λ_ex 370 nm; λ_em 420 nm (for cytoplasm of living cells), λ_ex 535 nm; λ_em 610 nm (for chromatin of living cells)	fluorescence λ_ex 358 nm; λ_em 461 nm, λ_ex 392 nm; λ_em 410 nm in methanol	fluorescence -	fluorescence -
color pink to very dark red	color -	color white to orange	color faint brown to brown, and Orange to Dark Orange and Red to Very Dark Red
application(s) diagnostic assay manufacturing hematology histology	application(s) -	application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology
form powder	form solid	form powder	form powder
solubility chloroform: 20 mg/mL	solubility acetonitrile: soluble, methanol: soluble	solubility H₂O: 50 mg/mL	solubility H₂O: 1 mg/mL

Application

Dihydroethidium has been used as a superoxide probe in bovine pulmonary artery endothelial cell (BPAEC).[1] It has been used to check the in situ generation of ROS (reactive oxygen species).[2][3]

Redox indicator. Blue fluorescence until oxidized to ethidium.

Packaging

Packaged under Argon.

Other Notes

B-ring reduced analog of ethidium

related product

Product No.

Description

Pricing

06693

Timestrip Plus^™ -20 °C

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

D7008-10MG:
D7008-VAR:
D7008-10MG-PW:
D7008-BULK:

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Mitochondrial Stress and ROS

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