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Merck

G5146

D-(+)-Glucose

Hybri-Max, powder, BioReagent, suitable for hybridoma

Synonym(s):

Dextrose

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¥9,240

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¥29,470

¥9,240

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
NACRES:
NA.75
EC Number:
200-075-1
Beilstein/REAXYS Number:
1724615

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Product Name

D-(+)-Glucose, Hybri-Max, powder, BioReagent, suitable for hybridoma

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

biological source

maize

grade

Hybri-Max

product line

BioReagent

assay

≥99.5%

form

powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

mp

150-152 °C (lit.)

solubility

H2O: 2g + 15 mL (Tested)

Quality Level

Gene Information

human ... PYGM(5837)

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This Item
G7021G7528G5767
biological source

maize

biological source

-

biological source

maize

biological source

wheat

grade

Hybri-Max

grade

-

grade

-

grade

ACS reagent

assay

≥99.5%

assay

≥99.5%

assay

≥99.5% (GC)

assay

-

technique(s)

cell culture | hybridoma: suitable

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

technique(s)

gas chromatography (GC): suitable

technique(s)

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

solubility

H2O: 2g + 15 mL (Tested)

solubility

H2O: 2g + 15 mL (Tested)

solubility

H2O: 1 M

solubility

-

Application

D-(+)-Glucose has been used in cell engineering.[1] It has also been used to perform oral glucose tolerance test.[2]

Biochem/physiol Actions

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia.[3] Mutation in PYGM leads to McArdle disease, a glycogen storage disorder.[4] The PYGM gene is significantly associated with energy production.[5]

General description

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively.[3] The PYGM gene is mapped to human chromosome 11q13.1.[6]

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

comparable product

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)


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Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: different effects on muscle and fat tissue insulin signaling
Johansson J, et al.
PLoS ONE, 8(1) (2013)
Comparative metabolic analysis of CHO cell clones obtained through cell engineering, for IgG productivity, growth and cell longevity
Wilkens CA and Gerdtzen ZP
PLoS ONE, 10(3) (2015)
The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia
Pinacho R, et al.
Schizophrenia Research, 177(1-3), 37-43 (2016)
Genetic evaluation of AMPD1, CPT2, and PGYM metabolic enzymes in patients with chronic fatigue syndrome
Maltese PE, et al.
Genetics and molecular research : GMR, 15(3), 1-10 (2016)
Novel variant in the PYGM gene causing late-onset limb-girdle myopathy, ptosis, and camptocormia
Cheraud C, et al.
Muscle and Nerve, 57(1), 157-160 (2018)

Articles

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

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