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L1663

Lidocaine N-ethyl chloride

sodium channel blocker

Synonym(s):

N-(2,6-Dimethylphenylcarbamoylmethyl) triethylammonium chloride

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About This Item

Empirical Formula (Hill Notation):
C16H27N2OCl
CAS Number:
5369-03-9
Molecular Weight:
298.85
UNSPSC Code:
12352200
PubChem Substance ID:
24896288
NACRES:
NA.77
MDL number:
MFCD01669894
Quality level:
100
Storage condition:
protect from light
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Product Name

Lidocaine N-ethyl chloride,

storage condition

protect from light

Quality Level

100

solubility

H2O: soluble

storage temp.

room temp

SMILES string

[Cl-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C16H26N2O.ClH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H

InChI key

LLPPOMUAOGMYQI-UHFFFAOYSA-N

Biochem/physiol Actions

Lidocaine N-ethyl chloride is an intracellular voltage-gated sodium channel blocker.

Other Notes

Stable at room temperature lyophilized. In solution, store at 4 °C for up to two weeks. Store solutions at -20 °C for up to six months.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

L1663-BULK: + L1663-1G: + L1663-500MG-PW: + L1663-500MG: + L1663-1G-PW: + L1663-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX6385
MKCV7873
MKCW4809
MKCV6533
MKCQ9042

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Vijay K Samineni et al.
Nature communications, 10(1), 4356-4356 (2019-09-27)
Itch is a distinct aversive sensation that elicits a strong urge to scratch. Despite recent advances in our understanding of the peripheral basis of itch, we know very little regarding how central neural circuits modulate acute and chronic itch processing.
Sung-Min Hwang et al.
Biomolecules, 10(11) (2020-11-11)
Local anesthetics (LAs) can completely block nociception by inhibiting voltage-gated sodium channels (VGSCs), and thus, blocking action potentials (APs) within sensory neurons. As one of the several LAs, eugenol is used for dental pain treatment. It reportedly features multiple functions
Iina Korkka et al.
Stem cells translational medicine, 8(2), 179-193 (2018-11-06)
Retinal pigment epithelium (RPE) performs important functions for the maintenance of photoreceptors and vision. Malfunctions within the RPE are implicated in several retinal diseases for which transplantations of stem cell-derived RPE are promising treatment options. Their success, however, is largely
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Global Trade Item Number

SKUGTIN
L1663-1G04061826226247
L1663-500MG04061832574783