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L1750

Sigma-Aldrich

L-(+)-Lactic acid

≥98%

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Synonym(s):
(S)-2-Hydroxypropionic acid, Sarcolactic acid
Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
Molecular Weight:
90.08
Beilstein:
1720251
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Assay

≥98%

antibiotic activity spectrum

Gram-negative bacteria

Mode of action

cell membrane | interferes

storage temp.

2-8°C

SMILES string

C[C@H](O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

InChI key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

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1 of 4

This Item
199257277151.00366
L-(+)-Lactic acid ≥98%

Sigma-Aldrich

L1750

L-(+)-Lactic acid

L-(+)-Lactic acid 80%

Sigma-Aldrich

27715

L-(+)-Lactic acid

(S)-Lactic acid about 90%, EMPROVE® EXPERT, Ph. Eur., BP, E 270

SAFC

1.00366

(S)-Lactic acid

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

2-25°C

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

500

antibiotic activity spectrum

Gram-negative bacteria

antibiotic activity spectrum

-

antibiotic activity spectrum

Gram-negative bacteria

antibiotic activity spectrum

-

mode of action

cell membrane | interferes

mode of action

-

mode of action

cell membrane | interferes

mode of action

-

General description

L-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactis produces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81).

Application

Lactic acid has been used:
  • as a component in substrate solution II for lactate dehydrogenase reaction
  • as an additive in storage solution A
  • as a supplement in the artificial gastric juice preparation for evaluation of degree of resistance Lactobacillus to the gastric stresses

Biochem/physiol Actions

L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

Supplementary Hazards

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110.00 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names


Certificates of Analysis (COA)

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Lactic acid United States Pharmacopeia (USP) Reference Standard

USP

1356734

Lactic acid

Lactic acid Pharmaceutical Secondary Standard; Certified Reference Material

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PHR1215

Lactic acid

Sodium L-lactate ~98%

Sigma-Aldrich

L7022

Sodium L-lactate

DL-Lactic acid 85 % (w/w), syrup

Sigma-Aldrich

L1250

DL-Lactic acid

Sodium L-lactate ≥99.0% (NT)

Sigma-Aldrich

71718

Sodium L-lactate

(S)-Lactic acid about 90%, EMPROVE® EXPERT, Ph. Eur., BP, E 270

SAFC

1.00366

(S)-Lactic acid

International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands
Davenport AP, et al.
Pharmacological Reviews, 65(3), 967-986 (2013)
A History of Lactic Acid Making: A Chapter in the History of Biotechnology (1990)
Cell-free transcription of SV40
SV40 protocols, 73-73 (2001)
The isolation, identification and analyzes of Lactobacillus genus bacteria with probiotic potential
Advances in Microbiology, Infectious Diseases and Public Health, 73-73 (2016)
Mastoparan as a G protein activator
Animal Toxins: Facts and Protocols, 120-121 (2000)

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