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L-Ornithine L-aspartate salt

Name: <SC>L</SC>-Ornithine <SC>L</SC>-aspartate salt
Brand: SIGMA
Price: 22300 JPY

≥98% (TLC)

Synonym(s):

(S)-2,5-Diaminopentanoic acid L-aspartate salt

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Pack Size	SKU	Availability	Price
25 g		Check Cart for Availability	¥22,300

About This Item

Empirical Formula (Hill Notation):

C₉H₁₉N₃O₆

CAS Number:

3230-94-2

Molecular Weight:

265.26

NACRES:

NA.26

PubChem Substance ID:

329818920

UNSPSC Code:

12352209

EC Number:

221-772-7

MDL number:

MFCD00058084

¥22,300

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Properties

Product Name

L-Ornithine L-aspartate salt, powder

assay

≥98% (TLC)

Quality Level

200

form

powder

color

white to off-white

storage temp.

2-8°C

SMILES string

NCCC[C@H](N)C(O)=O.N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C5H12N2O2.C4H7NO4/c6-3-1-2-4(7)5(8)9;5-2(4(8)9)1-3(6)7/h4H,1-3,6-7H2,(H,8,9);2H,1,5H2,(H,6,7)(H,8,9)/t4-;2-/m00/s1

InChI key

IXUZXIMQZIMPSQ-ZBRNBAAYSA-N

Description

Biochem/physiol Actions

L-Ornithine L-aspartate is a metabolite of arginine degradation by arginase. It has been shown to reduce blood ammonia concentrations by increasing ammoniadetoxification in the muscle and reducing the severity of hepatic encephalopathy in cirrhosis.

Other Notes

Product of arginine degradation by arginase

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1 of 1

This Item	O2375	O4386	75490
Sigma-Aldrich O7125 L-Ornithine L-aspartate salt	Sigma-Aldrich O2375 L-Ornithine monohydrochloride	Sigma-Aldrich O4386 L-Ornithine monohydrochloride	Sigma-Aldrich 75490 DL-Ornithine monohydrochloride
form powder	form powder	form powder	form powder
assay ≥98% (TLC)	assay ≥99%	assay ≥99%	assay ≥99.0% (AT)
storage temp. 2-8°C	storage temp. -	storage temp. -	storage temp. -
color white to off-white	color white	color white	color -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

O7125-100G: + O7125-VAR: + O7125-5G: + O7125-BULK: + O7125-25G:

jan

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Certificates of Analysis (COA)

Lot/Batch Number

0000456907

0000369173

SLBW4848

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A randomized controlled trial comparing lactulose, probiotics, and L-ornithine L-aspartate in treatment of minimal hepatic encephalopathy.

Vibhu Vibhas Mittal et al.

European journal of gastroenterology & hepatology, 23(8), 725-732 (2011-06-08)

Minimal hepatic encephalopathy (MHE) impairs daily functioning and health-related quality of life (HRQoL). The modalities of treatment of MHE have not been adequately studied. To compare lactulose, probiotics, and L-ornithine L-aspartate (LOLA) in treatment of MHE and effect on HRQoL

L-Ornithine-l-aspartate in the management of hepatic encephalopathy: a meta-analysis.

Qian Jiang et al.

Journal of gastroenterology and hepatology, 24(1), 9-14 (2008-10-01)

Hepatic encephalopathy continues to be a major clinical problem and the current decade has not witnessed major therapeutic breakthroughs in this area. L-ornithine-l-aspartate (LOLA) is not frequently used as there are still some reservations about its benefits. The present study

Oral L-ornithine-L-aspartate improves health-related quality of life in cirrhotic patients with hepatic encephalopathy: an open-label, prospective, multicentre observational study.

Janus P Ong et al.

Clinical drug investigation, 31(4), 213-220 (2011-01-07)

Hepatic encephalopathy (HE) is a serious complication of cirrhosis. Clinical trials have consistently shown that L-ornithine-L-aspartate significantly improves HE symptoms. Health-related quality of life (HR-QOL) is impaired in HE patients and represents an important outcome measure for therapeutic intervention. The

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Global Trade Item Number

SKU	GTIN
O7125-25G	04061834248392
O7125-100G	04061834248385

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Key Documents

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L-Ornithine L-aspartate salt

≥98% (TLC)

Select a Size

About This Item

¥22,300

Product Name

assay

Quality Level

form

color

storage temp.

SMILES string

InChI

InChI key

Biochem/physiol Actions

Other Notes

Compare Similar Items

This Item

Safety Information

Storage Class

wgk

flash_point_f

flash_point_c

ppe

Regulatory Listings

O7125-100G: + O7125-VAR: + O7125-5G: + O7125-BULK: + O7125-25G:

Documentation

Certificates of Analysis (COA)

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