SML1663

Butoconazole nitrate

≥90% (HPLC)

• Synonym(s): 1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole,nitric acid, Exelgyn, Femstat One, Gynazole-1, Gynomyk, (±)-1-[4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole mononitrate
• Empirical Formula (Hill Notation): C₁₉H₁₇Cl₃N₂S · HNO₃
• CAS Number: 64872-77-1
• Molecular Weight: 474.79
• NACRES: NA.77
• PubChem Substance ID: 329826001
• UNSPSC Code: 12352200
• MDL number: MFCD00058159
• Assay: ≥90% (HPLC)
• Form: powder

Properties

• Quality Segment: 200
• assay: ≥90% (HPLC)
• form: powder
• solubility: DMSO or DMF: soluble, methanol: soluble
• storage temp.: 2-8°C
• SMILES string: ClC1=C(C(Cl)=CC=C1)SC(CCC2=CC=C(Cl)C=C2)CN3C=CN=C3.O[N+]([O-])=O
• InChI: 1S/C19H17Cl3N2S.HNO3/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22;2-1(3)4/h1-5,7-8,10-11,13,16H,6,9,12H2;(H,2,3,4)
• InChI key: ZHPWRQIPPNZNML-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Butoconazole is an imidazole derivative with in vitro antifungal activity against Candida spp. In addition, Butoconazole is clinically effective against vaginal infections. The exact mechanism for its activity is unknown. However, Butoconazole was found to interfere with the biosynthesis of lipid and ergosterol.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable