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WR-1065

Name: WR-1065
Brand: SIGMA
Price: 21500 JPY
Availability: InStock

≥98% (HPLC), reactive oxygen species scavenger, powder

Synonym(s):

2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride, WR-1065 dihydrochloride

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Size/SKU	Availability	Price
10 mg	Estimated to ship TODAYfromsìså¬368	¥21,500
50 mg	Check Cart for Availability	¥67,500

About This Item

Empirical Formula (Hill Notation):

C₅H₁₄N₂S · 2HCl

CAS Number:

14653-77-1

Molecular Weight:

207.16

UNSPSC Code:

12352200

PubChem Substance ID:

329830444

NACRES:

NA.77

MDL number:

MFCD00460339

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated

¥21,500

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Properties

Product Name

WR-1065, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

solubility

H₂O: ≥20 mg/mL

storage temp.

−20°C

SMILES string

Cl.Cl.NCCCNCCS

InChI

1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H

InChI key

XDRLRDHLCIFZIW-UHFFFAOYSA-N

Description

Biochem/physiol Actions

WR-1065 is a cytoprotective cell-permeable ROS scavenge and an active metabolite of Amifostine.

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

WR-1065 is the active metabolite of the prodrug amifostine, generated by alkaline phosphatase. It is found to accumulate in many epithelial tissues. WR-1065 protects cellular membranes and DNA from free radical induced damage.

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This Item	SML0276	SML0635	SML1158
Sigma-Aldrich W2020 WR-1065	Sigma-Aldrich SML0276 BD 1063 dihydrochloride	Sigma-Aldrich SML0635 AZD6765 dihydrochloride	Sigma-Aldrich SML1158 (2S)-Hypusine dihydrochloride
description ≥98% (HPLC)	description ≥98% (HPLC)	description ≥97% (HPLC)	description ≥95% (HPLC)
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥97% (HPLC)	assay ≥95% (HPLC)
form powder	form powder	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. room temp	storage temp. 2-8°C	storage temp. −20°C
storage condition desiccated	storage condition desiccated	storage condition desiccated	storage condition desiccated
solubility H₂O: ≥20 mg/mL	solubility H₂O: >15 mg/mL	solubility H₂O: 20 mg/mL, clear	solubility H₂O: 15 mg/mL, clear

pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H318

pcodes

P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

W2020-VAR: + W2020-50MG: + W2020-BULK: + W2020-10MG: + W2020-IP:

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