- Synthesis and free radical scavenging activity of some new spiropyranocoumarins.
Synthesis and free radical scavenging activity of some new spiropyranocoumarins.
Bioorganic & medicinal chemistry letters (2008-10-07)
Vassiliki Panteleon, Ioannis K Kostakis, Panagiotis Marakos, Nicole Pouli, Ioanna Andreadou
PMID18835711
要旨
A series of novel spiro-substituted 4-hydroxypyranocoumarins and their corresponding dihydropyrano cis-diols has been synthesized. Among them the spiroadamantylpyranocoumarin and the diols can interact with the stable free radical 1,1-diphenyl-2-picrylhydrazyl and scavenge superoxide anions generated in the xanthine-xanthine oxidase system.
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