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Molecular imprinted magnetic nanoparticles for controlled delivery of mitomycin C.

Molecular imprinted magnetic nanoparticles for controlled delivery of mitomycin C.

Artificial cells, nanomedicine, and biotechnology (2013-08-14)

Deniz Türkmen, Nilay Bereli, M Emin Çorman, Huma Shaikh, Sinan Akgöl, Adil Denizli

要旨

Controlled drug delivery system is a technique which has considerable recent potential in the fields of pharmacy and medicine. Mitomycin C is commonly used drug in the treatment of superficial bladder and breast cancers. In the present study, mitomycin C-imprinted magnetic poly(hydroxyethyl methacrylate)-based nanoparticles (MIMNs) were prepared using surfactant free emulsion polymerization for controlled delivery of mitomycin C. The MIMNs were characterized by fourier transform infrared spectroscopy, scanning electron microscopy, atomic force microscopy, electron spin resonance, and elemental analysis. The average particle diameter of MIMNs was about 200 nm.

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製品内容

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過硫酸カリウム, ACS reagent, ≥99.0%

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メタクリル酸2-ヒドロキシエチル, ≥99%, contains ≤50 ppm monomethyl ether hydroquinone as inhibitor

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ジメタクリル酸エチレングリコール, 98%, contains 90-110 ppm monomethyl ether hydroquinone as inhibitor

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ペルオキソ二硫酸カリウム, puriss. p.a., ACS reagent, ≥99.0% (RT)

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メタクリル酸2-ヒドロキシエチル, contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%

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酸化鉄(II,III), nanopowder, 50-100 nm particle size (SEM), 97% trace metals basis

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酸化鉄(II,III), powder, <5 μm, 95%

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過硫酸カリウム, 99.99% trace metals basis

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酸化鉄(II,III), 99.99% trace metals basis

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酸化鉄(II,III)、磁性ナノ粒子溶液, 10 nm avg. part. size, 5 mg/mL in toluene

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酸化鉄(II,III)、磁性ナノ粒子溶液, 30 nm avg. part. size (TEM), PEG functionalized, dispersion, 1 mg/mL Fe in H₂O

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酸化鉄(II,III)、磁性ナノ粒子溶液, 10 nm avg. part. size, 5 mg/mL in H₂O

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酸化鉄(II,III)、磁性ナノ粒子溶液, 5 nm avg. part. size, 5 mg/mL in H₂O

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酸化鉄(II,III)、磁性ナノ粒子溶液, 10 nm avg. part. size (TEM), carboxylic acid functionalized, 5 mg/mL Fe in H₂O, dispersion

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酸化鉄(II,III)、磁性ナノ粒子溶液, 20 nm avg. part. size, 5 mg/mL in H₂O

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酸化鉄(II,III)、磁性ナノ粒子溶液, 30 nm avg. part. size (TEM), amine functionalized, 1 mg/mL Fe in H₂O, dispersion

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メタクリル酸2-ヒドロキシエチル

Sigma-Aldrich

酸化鉄(II,III)、磁性ナノ粒子溶液, 5 nm avg. part. size, 5 mg/mL in toluene

Sigma-Aldrich

酸化鉄(II,III)、磁性ナノ粒子溶液, 20 nm avg. part. size, 5 mg/mL in toluene

Sigma-Aldrich

酸化鉄(II,III)、磁性ナノ粒子溶液, 10 nm avg. part. size (TEM), PEG functionalized, 1 mg/mL Fe in H₂O, dispersion

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酸化鉄(II,III)、磁性ナノ粒子溶液, 10 nm avg. part. size (TEM), amine functionalized, 1 mg/mL Fe in H₂O, dispersion

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ペルオキソ二硫酸カリウム, suitable for determination of nitrogen and phosphorus, ≥99.0%

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酸化鉄(II,III)、磁性ナノ粒子溶液, 5 nm avg. part. size (TEM), PEG functionalized, 1 mg/mL Fe in H₂O, dispersion

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ペルオキソ二硫酸カリウム, JIS special grade, ≥98.0%