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Merck

TUBA1A

tubulin, alpha 1a

동의어:
B-ALPHA-1, LIS3, TUBA3
:
UniProtKB ID:
Clone ID:
  • Human(7846) Summary: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
  • Mouse(22142) tubulin, alpha 1A
  • Rat(64158) tubulin, alpha 1A
  • Horse(100051840) tubulin, alpha 1a
  • cow(404053) tubulin, alpha 1a
  • domestic cat(101096902) tubulin, alpha 1a
  • dog(608147) tubulin, alpha 1a
  • domestic guinea pig(100726777) tubulin, alpha 1a

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-alpha-Tubulin antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM113, purified immunoglobulin,
종별 반응성
all
응용분야
ChIP
ELISA

flow cytometry

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-monoglycylated Tubulin Antibody, clone TAP 952, clone TAP 952, from mouse,
종별 반응성
drosophila, human, mouse, porcine, sea urchin, sheep, snail
응용분야
dot blot
immunofluorescence

western blot
Anti-acetyl-alpha tubulin Antibody, clone 6-11B-1, clone 6-11B-1, from mouse,
종별 반응성
chlamydomonas, drosophila, bovine, human, monkey, mouse, rat-kangaroo, sea urchin
응용분야
dot blot
electron microscopy

immunocytochemistry

western blot
Anti-α-Tubulin Antibody, clone DM1A, Alexa Fluor 647 conjugate, clone DM1A, from mouse, ALEXA FLUOR 647,
종별 반응성
avian, bovine, gerbil, guinea pig, human, mouse, porcine, rat
응용분야
immunocytochemistry
Anti-pan polyglycylated Tubulin Antibody, clone AXO 49, clone AXO 49, from mouse,
종별 반응성
apis, drosophila, paramecium, lemur, mouse, pig, porcine, protista, sea urchin, sheep, snail, trout
응용분야
dot blot
immunofluorescence

western blot

Small Molecule - Inhibitor

제품 번호
설명
Docetaxel, purum, ≥97.0% (HPLC),
human
Paclitaxel semi-synthetic for peak identification, European Pharmacopoeia (EP) Reference Standard,
human
Taxol, phyproof® Reference Substance,
human
Colchicine for system suitability A, European Pharmacopoeia (EP) Reference Standard,
human
Vinblastine sulfate, European Pharmacopoeia (EP) Reference Standard,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Tuba1a,
mouse
MISSION® esiRNA, targeting human TUBA1A,
human