SAB4503087

Anti-WASP antibody produced in rabbit

affinity isolated antibody

• Sinónimos: IMD2, WAS, Wiskott-Aldrich syndrome protein, Wiskott-Aldrich syndrome protein homolog
• NACRES: NA.41
• UNSPSC Code: 12352203

Propiedades

• Nombre del producto: Anti-WASP antibody produced in rabbit, affinity isolated antibody
• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 52 kDa
• species reactivity: human, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P42768
• UniProt accession no.: P42768
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Quality Level: 100
• Gene Information: human ... WAS(7454)

Descripción

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

General description

WASP (Wiskott-Aldrich syndrome protein) codes for a 65 kDa protein, localized to the cytoplasm. The WASP gene is mapped to human chromosome Xp11.23.

Anti-WASP Antibody detects endogenous levels of total WASP protein.

Biochem/physiol Actions

WASP (Wiskott-Aldrich syndrome protein) is regarded as a scaffold protein that integrates cell surface signals to actin cytoskeleton. WASP gene regulates actin polymerization, contributing to T-cell activation and migration. Neural WASP is known to regulate a variety of cellular processes including pathogen infection, vesicle trafficking, invadopodium formation and growth, and neurite extension. Mutation in this gene causes WAS, a X-linked recessive immunodeficiency disorder.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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Immunogen

The antiserum was produced against synthesized peptide derived from human WASP.

Immunogen Range: 256-305

Información de seguridad

• Clase de almacenamiento: 10 - Combustible liquids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable