Methimazole embryopathy: delineation of the phenotype.

American journal of medical genetics (1999-03-17)
M Clementi, E Di Gianantonio, E Pelo, I Mammi, R T Basile, R Tenconi
RESUMEN

We report on a further case of congenital anomalies in a child exposed to methimazole during the first trimester of pregnancy (from first to seventh gestational week), and define a specific malformation pattern related to prenatal methimazole exposure and consisting of choanal and esophageal atresia, scalp defects, minor facial anomalies and psychomotor delay.

MATERIALES
Referencia del producto
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Descripción del producto

Supelco
Methimazole, analytical standard
Sigma-Aldrich
2-Mercapto-1-methylimidazole, ≥99%
Supelco
Methimazole, VETRANAL®, analytical standard
Thiamazole, European Pharmacopoeia (EP) Reference Standard
USP
Methimazole, United States Pharmacopeia (USP) Reference Standard