A6558

L-Aspartic acid potassium salt

Name: <SC>L</SC>-Aspartic acid potassium salt
Brand: SIGMA

≥98% (HPLC), suitable for ligand binding assays

Synonym(s):

Potassium L-aspartate

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About This Item

Linear Formula:

HO₂CCH₂CH(NH₂)CO₂K

CAS Number:

1115-63-5

Molecular Weight:

171.19

UNSPSC Code:

12352209

eCl@ss:

32160406

PubChem Substance ID:

24891105

NACRES:

NA.77

EC Number:

214-226-4

MDL number:

MFCD00063085

Key Documents

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Product Name

L-Aspartic acid potassium salt, ≥98% (HPLC)

SMILES string

N[C@H](C([O-])=O)CC(O)=O.[K+]

InChI

1S/C4H7NO4.K/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H,6,7)(H,8,9);/q;+1/p-1/t2-;/m0./s1

InChI key

TXXVQZSTAVIHFD-DKWTVANSSA-M

assay

≥98% (HPLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white

Quality Level

200

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Amino Acids

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Show Differences

1 of 4

This Item	11195	A6683	11240
Sigma-Aldrich A6558 L-Aspartic acid potassium salt	Sigma-Aldrich 11195 L-Aspartic acid sodium salt monohydrate	Sigma-Aldrich A6683 L-Aspartic acid sodium salt monohydrate	Sigma-Aldrich 11240 DL-Aspartic acid potassium salt hemihydrate
form powder	form powder or crystals	form powder	form powder or crystals
technique(s) ligand binding assay: suitable	technique(s) -	technique(s) -	technique(s) -
assay ≥98% (HPLC)	assay ≥99.0% (NT)	assay ≥98% (TLC)	assay ≥98.0% (NT)
color white	color white	color white	color white
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100

Application

L-Aspartic acid potassium salt has been used:

to prepare perforated patch-clamp intracellular solution
in serum glutamate–oxaloacetate transaminase (SGOT) assay
as a component in an internal solution (IS) for mitoflash assay to detect mitochondrial flashes in permeabilized cells

Biochem/physiol Actions

L-Aspartic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist.

Potassium aspartate is capable of preventing ventricular arrhythmia in ischemic rabbit heart by decreasing transmural repolarization dispersion (TDR).

Principal neurotransmitter for fast synaptic excitation.

General description

L-aspartic acid is a non-essential amino acid.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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l-aspartic acid promotes fish survival against Vibrio alginolyticus infection through nitric oxide-induced phagocytosis.

Qiyang Gong et al.

Fish & shellfish immunology, 97, 359-366 (2019-12-24)

Bacterial infection severely impairs aquaculture development throughout the world. Despite the use of antibiotics to control bacterial infection, few other options are available especially in the area of complex ecosystem and various types of fish. In search for novel approaches

Effects of potassium aspartate and magnesium on ventricular arrhythmia in ischemia-reperfusion rabbit heart.

Jun Pu et al.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 28(5), 517-519 (2008-10-11)

The aim of this study was to determine if the potassium aspartate and magnesium (PAM) prevent reperfusion-induced ventricular arrhythmias (RIVA) in ischemia-reperfusion (IR) rabbit heart. Thirty rabbits were randomly divided into control, ischemia and PAM groups. Arterially-perfused rabbit left ventricular

Whole-cell and Perforated Patch-clamp Recordings from Acutely-isolated Murine Sino-atrial Node Cells.

Qadeer Aziz et al.

Bio-protocol, 10(1), e3478-e3478 (2020-01-05)

Cardiac pacemaker cells of the sino-atrial node are responsible for the initiation of the heart beat and express an array of ion channels. The patch-clamp technique is the gold standard method for investigating the function of ion channels expressed in

Assessment of antioxidant activity of eugenol in vitro and in vivo.

Enika Nagababu et al.

Methods in molecular biology (Clifton, N.J.), 610, 165-180 (2009-12-17)

Reactive oxygen species are implicated in many human diseases and aging process. Much of the evidence is based on experimental data indicating increasing rates of lipid peroxidation in disease states and the ameliorating effects of antioxidants. It is becoming increasingly

Programmable Gene Knockdown in Diverse Bacteria Using Mobile-CRISPRi.

Amy B Banta et al.

Current protocols in microbiology, 59(1), e130-e130 (2020-12-18)

Facile bacterial genome sequencing has unlocked a veritable treasure trove of novel genes awaiting functional exploration. To make the most of this opportunity requires powerful genetic tools that can target all genes in diverse bacteria. CRISPR interference (CRISPRi) is a

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