A8380

5α-Androstan-17β-ol-3-one

synthetic, ≥97.5%, Androgen hormone, powder

• Synonym(s): 17β-Hydroxy-5α-androstan-3-one, 4,5α-Dihydrotestosterone, Androstanolone, Stanolone
• Empirical Formula (Hill Notation): C₁₉H₃₀O₂
• CAS Number: 521-18-6
• Molecular Weight: 290.44
• NACRES: NA.77
• PubChem Substance ID: 24891337
• UNSPSC Code: 51111800
• EC Number: 208-307-3
• MDL number: MFCD00003667
• Beilstein/REAXYS Number: 2056371

Properties

• Product Name: 5α-Androstan-17β-ol-3-one, ≥97.5%
• InChI key: NVKAWKQGWWIWPM-ABEVXSGRSA-N
• InChI: 1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1
• SMILES string: [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CCC(=O)C2
• biological source: synthetic
• sterility: non-sterile
• assay: ≥97.5%
• form: powder
• drug control: USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• solubility: ethanol: 50 mg/mL, clear to slightly hazy, colorless to very faintly yellow
• Quality Level: 200
• Gene Information: human ... AR(367), ESR1(2099), PGR(5241), SERPINA6(866), SHBG(6462) ; mouse ... Esr1(13982) ; rat ... Ar(24208), Esr1(24890), Nr3c1(24413), Nr3c2(25672), Pgr(25154)

Description

Application

5α-Androstan-17β-ol-3-one, also referred to as androstanolone or dihydrotestosterone, is an anabolic steroid. Testosterone secreted by the testis is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone, including the development of the male phenotype during embryogenesis and at puberty.

Biochem/physiol Actions

Androstanolone is an anabolic steroid. Testosterone secreted by the testis is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone. Androgens direct the development of the male phenotype during embryogenesis and at puberty.

Safety Information

• pictograms: GHS08,GHS07,GHS09
• signalword: Danger
• hcodes: H302,H351,H360FD,H410
• pcodes: P202 - P264 - P270 - P273 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Repr. 1A
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges