ESR1
estrogen receptor 1
別名:
ER, ESR, ESRA, ESTRR, Era, NR3A1
Species:
Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), domestic cat ESR1 (552888), dog ESR1 (403640), chicken ESR1 (396099), Thale Cress ESR1 (837856), Horse ESR1 (791249), Zebrafish esr1 (259252), cow ESR1 (407238) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
- Mouse(13982) estrogen receptor 1 (alpha)
- Rat(24890) estrogen receptor 1
- domestic cat(552888) estrogen receptor 1
- dog(403640) estrogen receptor 1
- chicken(396099) estrogen receptor 1
- Thale Cress(837856) ethylene-responsive transcription factor ESR1
- Horse(791249) estrogen receptor 1
- Zebrafish(259252) estrogen receptor 1
- cow(407238) estrogen receptor 1
- Goat(100860768) estrogen receptor 1
- sheep(443228) estrogen receptor 1
- domestic guinea pig(100713276) estrogen receptor 1
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Small Molecule - Activator
製品番号
詳細
Species
β-ニコチンアミドアデニンジヌクレオチド 水和物, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
Species
human
Small Molecule - Agonist
製品番号
詳細
Species
17β-エストラジオール 溶液, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
17α-エチニルエストラジオール, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Small Molecule - Allosteric Modulator
製品番号
詳細
Species
タモキシフェン, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human
Small Molecule - Antagonist
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-Estrogen Receptor α Antibody, clone F3-A, ascites fluid, clone F3-A, from mouse,
交差性
human, mouse, rat
アプリケーション
immunocytochemistry
western blot
western blot
抗ESR1 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Estradiol Antibody, clone 6E1, ascites fluid, clone 6E1, Chemicon®,
交差性
human
アプリケーション
ELISA
Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗エストロゲン関連受容体α抗体, Upstate®, from rabbit,
交差性
hamster, human, mouse, rat
アプリケーション
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
Small Molecule - Mixed Agonist/Antagonist
製品番号
詳細
Species
Proteins
製品番号
詳細
Species
エストロゲンレセプターα ヒト, ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human