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Merck

C5679

Casein from bovine milk

BioReagent, suitable for insect cell culture

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500 G

$249.00

$249.00


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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.75
EC Number:
232-555-1
MDL number:

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Product Name

Casein from bovine milk, BioReagent, suitable for insect cell culture

SMILES string

[P](=O)(OCC(NC(=O)C(NC(=O)C(N)Cc1ccccc1)CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(C(O)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C

InChI key

BECPQYXYKAMYBN-UHFFFAOYSA-N

InChI

1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)

biological source

bovine milk

product line

BioReagent

form

powder

technique(s)

cell culture | insect: suitable

mp

280 °C (dec.) (lit.)

UniProt accession no.

Quality Level

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1 of 4

This Item
1.02241C7078SRE0040
biological source

bovine milk

biological source

-

biological source

bovine milk

biological source

bovine

technique(s)

cell culture | insect: suitable

technique(s)

-

technique(s)

activity assay: suitable, electrophoresis: suitable, immunocytochemistry: suitable

technique(s)

-

form

powder

form

-

form

powder

form

powder

UniProt accession no.

P02662, P02666, P02663, P02668

UniProt accession no.

-

UniProt accession no.

P02662, P02663, P02666

UniProt accession no.

P02662, P02663, P02666, P02668

Gene Information

bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099), CSN3(281728)

Gene Information

-

Gene Information

bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099)

Gene Information

bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099), CSN3(281728)

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

400

Analysis Note

essentially vitamin free

Application

Casein from bovine milk has been used as a component of normal medium for Drosophila culture [1], in the preparation of αS1-casein (CAS1_Bovin) [2], as a source of nitrogen (N) in experiment diets [3].

Biochem/physiol Actions

Numerous experimental applications including use as a blocking agent in immunochemistry, recovery of enzyme activity from SDS extracted samples, and as a substrate for protease and kinase assays.
Partial gastrointestinal digestion of casein is a rich source of bioactive peptides, such as β-casomorphin. However, bovine casein is not homogeneous; variants A1 and B do lead to production of β-casomorphin 7 production, while A2 does not.

General description

Casein is a calcium phosphate-binding phosphoprotein present in mammalian milk. It constitutes about 80% of the total bovine milk.[4] Bovine milk is made of four types of casein such as, αs1-, αs2-, β-, and κ-caseins.[5]

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)


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Casein and Peptides Derived from Casein as Antileukaemic Agents
Ledesma M E, et al.
Journal of Oncology, 2019(4), 71-71 (2019)
The effects of rumen nitrogen balance on in vitro rumen fermentation and microbial protein synthesis vary with dietary carbohydrate and nitrogen sources
Kand D, et al.
Anim. Feed Sci. Technol., 241(12) (2018)
Potential of casein as a carrier for biologically active agents
Glkab T K and Boratynski J
Topics in Current Chemistry, 375(4), 71-71 (2017)
S Elsayed et al.
Molecular immunology, 41(12), 1225-1234 (2004-10-16)
T cell recognition patterns of CAS1_Bovin, its limited hydrolysis, oxidized, reduced/alkylated, cyanogen bromide cleavage fractions and synthetic peptides were examined. Thirteen overlapping peptides covering the intact molecule, with chain lengths varied between 17 and 20 AA, were prepared by f-moc
Effects of synthetic diets enriched in specific nutrients on Drosophila development, body fat, and lifespan
Reis T
Testing, 11(1), 71-71 (2016)

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