1.06007

Methanol

≥99.9% (GC), gradient grade, suitable for HPLC, LiChrosolv^®, reag. Ph. Eur.

• Synonym(s): Methyl alcohol
• Linear Formula: CH₃OH
• CAS Number: 67-56-1
• Molecular Weight: 32.04
• Beilstein: 1098229
• MDL number: MFCD00004595
• UNSPSC Code: 12191502
• EC Index Number: 200-659-6
• NACRES: NA.03
• Assay: ≥99.9% (GC)
• Technique(s): HPLC: suitable
• Bp: 64.7 °C (lit.)
• Vapor pressure: 128 hPa ( 20 °C); 410 mmHg ( 50 °C); 97.68 mmHg ( 20 °C)

Properties

• Product Name: Methanol, gradient grade for liquid chromatography LiChrosolv^® Reag. Ph Eur
• grade: gradient grade; gradient grade
• Quality Level: 200
• Agency: reag. Ph. Eur.
• vapor density: 1.11 (vs air)
• vapor pressure: 128 hPa ( 20 °C); 410 mmHg ( 50 °C); 97.68 mmHg ( 20 °C)
• product line: LiChrosolv^®
• Assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 725 °F
• potency: 5628 mg/kg LD₅₀, oral (Rat); 17100 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 36 %
• technique(s): HPLC: suitable
• impurities: ≤0.0002 meq/g Acidity; ≤0.0002 meq/g Alkalinity; ≤0.02% Water
• evapn. residue: ≤2.0 mg/L
• color: APHA: ≤10
• transmittance: 210 nm, ≥20%; 220 nm, ≥60%; 230 nm, ≥75%; 235 nm, ≥83%; 250 nm, ≥95%; 260 nm, ≥98%
• refractive index: n20/D 1.329 (lit.)
• kinematic viscosity: 0.54-0.59 cSt(20 °C)
• bp: 64.7 °C (lit.)
• mp: −98 °C (lit.)
• transition temp: flash point 9.7 °C
• density: 0.791 g/mL at 25 °C (lit.)
• UV absorption: λ: 225 nm A_max: ≤0.170
• format: neat
• storage temp.: 2-30°C
• SMILES string: CO
• InChI: 1S/CH4O/c1-2/h2H,1H3
• InChI key: OKKJLVBELUTLKV-UHFFFAOYSA-N

Description

General description

LiChrosolv^® solvents were specially formulated to meet the demanding needs of analytical HPLC applications. With exceptional UV transmittance, minimal particle count, and controlled acidity and alkalinity, our solvents ensure reproducible separations every time. The low evaporation residue level further enhances their performance, making them the ideal choice for high-quality results. The product line includes both "gradient grade" and "isocratic grade" solvents, specifically designed to reduce the gradient effect during separations. This tailored approach allows for optimal consistency and accuracy in your analytical processes, helping you achieve the best possible outcomes in your chromatography work.

Now Available with Data Matrix Code

This high-quality HPLC-grade solvent now features a unique Data Matrix Code on its label, providing digital access to essential product information such as batch number, product number, and expiry date. Unlike standard barcodes, our DMCs feature a unique serial number for each bottle, enabling you to monitor and trace every bottle individually. With standard barcodes, all bottles from the same batch look identical. Our solution gives you true bottle-level traceability for greater control and compliance in the lab.
Know more about our data matrix code-labeled HPLC-grade solvents.

Application

• Mobile Phase in HPLC: Widely utilized as a polarsolvent in both reversed-phase and normal-phase HPLC, suitable for varioustypes of analytes.
• Gradient Elution: Ideal for gradient elutiontechniques, enhancing the resolution and separation efficiency of complexmixtures.
• Pharmaceutical Quality Control: Used in the qualitycontrol of pharmaceutical products to analyze formulations, stability, anddegradation products.
• Food and Beverage Analysis: Employed in HPLC for theanalysis of additives, preservatives, and flavor compounds in food and beveragesamples.
• Natural Product Analysis: Utilized in the separationand characterization of natural products, such as alkaloids and flavonoids,from plant extracts.

Features and Benefits

• High Purity: Formulated with minimal impurities,ensuring reliable and reproducible results essential for sensitive analyticalapplications.
• Excellent UV Transparency: Provides optimal UVtransmittance, facilitating accurate detection and enhancing sensitivity inHPLC analyses.
• Low Evaporation Residue: Minimizes contaminationrisk, leading to cleaner separations and improved analytical reliability.
• Batch-to-Batch Consistency: Ensures uniform qualityand performance across different production batches, enhancing reproducibilityand confidence in analytical results.

Preparation Note

Microfilteredby 0.2 μm filter

Analysis Note

Evaporation Number: 1.9

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Evaporation residue: ≤ 2.0 mg/l
Water: ≤ 0.02 %
Color: ≤ 10 Hazen
Density (d 20 °C/20 °C): 0.791 - 0.793
Boiling point: 64 - 65 °C
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Gradient grade (at 235 nm): ≤ 2.0 mAU
Gradient grade (at 254 nm): ≤ 1.0 mAU
Fluorescence (as quinine at 254 nm): ≤ 1.0 ppb
Fluorescence (as quinine at 365 nm): ≤ 0.5 ppb
Transmission (at 210 nm): ≥ 20 %
Transmission (at 220 nm): ≥ 60 %
Transmission (at 230 nm): ≥ 75 %
Transmission (at 235 nm): ≥ 83 %
Transmission (at 250 nm): ≥ 95 %
Transmission (from 260 nm): ≥ 98 %
Absorbance (at 225 nm): ≤ 0.170
Filtered by 0.2 µm filter.
Suitable for UPLC / UHPLC /Ultra HPLC - instruments.
Conforms to Methanol R1 and R2 according to Reag. Ph Eur;
conforms to the requirements of ACS for liquid chromatography suitability.

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup