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1.06346
Sodium dihydrogen phosphate monohydrate
for analysis EMSURE® ACS,Reag. Ph Eur
Synonym(s):
Sodium phosphate monobasic monohydrate, Monosodium phosphate, Sodium dihydrogen phosphate monohydrate
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About This Item
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grade
ACS reagent
Quality Level
Agency
reag. Ph. Eur.
product line
EMSURE®
Assay
99.0-102.0% (alkalimetric)
form
crystals
potency
>2000 mg/kg LD50, oral (Rat)
>7940 mg/kg LD50, skin (Rabbit)
impurities
≤0.01% Insoluble matter
pH
4.1-4.5 (25 °C, 50 g/L in H2O)
solubility
850 g/L
density
2.04 g/cm3 at 20 °C
bulk density
880 kg/m3
anion traces
chloride (Cl-): ≤0.0005%
sulfate (SO42-): ≤0.003%
cation traces
Ca: ≤0.005%
Fe: ≤0.0005%
K: ≤0.005%
N: ≤0.001%
heavy metals: ≤0.0005%
UV absorption
λ: 280 nm Amax: ≤0.05
storage temp.
2-30°C
SMILES string
[Na+].[H]O[H].OP(O)([O-])=O
InChI
1S/Na.H3O4P.H2O/c;1-5(2,3)4;/h;(H3,1,2,3,4);1H2/q+1;;/p-1
InChI key
BBMHARZCALWXSL-UHFFFAOYSA-M
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This Item | S9638 | S3522 | 567545 |
|---|---|---|---|
| form crystals | form crystalline | form powder | form solid |
| assay 99.0-102.0% (alkalimetric) | assay ≥98%, 98.0-102.0% | assay 98.0-102.0% | assay ≥98% (by assay) |
| solubility 850 g/L | solubility - | solubility - | solubility water: soluble |
| Quality Level 300 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| grade ACS reagent | grade ACS reagent | grade - | grade ACS reagent |
| cation traces Ca: ≤0.005%, K: ≤0.005%, heavy metals: ≤0.0005%, Fe: ≤0.0005%, N: ≤0.001% | cation traces Ca: ≤0.005%, Fe: ≤0.001%, K: ≤0.01%, heavy metals: ≤0.001% (by ICP-OES) | cation traces Ca: ≤0.005%, Fe: ≤0.001%, K: ≤0.01%, heavy metals (as Pb): ≤0.001% | cation traces heavy metals: ≤0.001% |
Application
- Development of a multiparticulate drug delivery system for in situ amorphisation.: This study explores the use of sodium dihydrogen phosphate monohydrate in developing a multiparticulate drug delivery system. The research highlights the compound′s role in achieving in situ amorphisation, enhancing drug solubility and bioavailability (Holm TP et al., 2022).
- Metabolomic characterization of rhubarb species by capillary electrophoresis and ultra-high-pressure liquid chromatography.: Sodium dihydrogen phosphate monohydrate is utilized in the buffer system for capillary electrophoresis and UHPLC, aiding in the metabolomic analysis of rhubarb species. This research underscores its importance in improving separation efficiency and resolution in analytical methods (Tseng YJ et al., 2013).
Analysis Note
Insoluble matter: ≤ 0.01 %
pH-value (5 %; water, 25 °C): 4.1 - 4.5
UV absorption (280 nm; 1 mol/l; 1 cm; water): ≤ 0.05
Chloride (Cl): ≤ 0.0005 %
Sulfate (SO₄): ≤ 0.003 %
Total nitrogen (N): ≤ 0.001 %
Heavy metals (ACS): ≤ 0.0005 %
Ca (Calcium): ≤ 0.005 %
Fe (Iron): ≤ 0.0005 %
K (Potassium): ≤ 0.005 %
Corresponds to ACS,Reag. Ph Eur
Other Notes
Legal Information
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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