12667-M

Human Serum Albumin

30% Aqueous Solution

• Synonym(s): Albumin, Human Serum, 30% Aqueous Solution
• CAS Number: 70024-90-7
• UNSPSC Code: 12352202
• MDL number: MFCD00081418
• NACRES: NA.25

Properties

• Product Name: Albumin, Human Serum, 30% Aqueous Solution,
• SMILES string: FC(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
• InChI key: QYSGYZVSCZSLHT-UHFFFAOYSA-N
• biological source: human
• description: Merck USA index - 14, 8468
• assay: ≥95% (agarose gel electrophoresis)
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• technique(s): cell culture | mammalian: suitable
• storage temp.: 2-8°C
• Quality Level: 100

Description

Biochem/physiol Actions

Human serum albumin (HSA) acts as the most important carrier protein for fatty acids, thyroid hormones, and steroids.[1] It serves as a supplement in cell culture medium for the generation of vaccines and pharmaceuticals.[1] HSA acts as a valuable biomarker for diseases, such as severe acute graft-versus-host disease, cancer, and rheumatoid arthritis.[2] It is clinically used to treat serious burn injuries, hemorrhagic shock, hypoproteinemia, and fetal erythroblastosis.[1] HSA is used in biological applications including nano delivery of drugs, carrier of oxygen, and fusion of peptides.[1]

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Toxicity: Standard Handling (A)

General description

Human serum albumin (HSA) is a soluble, globular, and unglycosylated monomeric protein,[1] which is abundantly found in the plasma.[2] It contains three homologous domains, numbered I, II, and III.[3] Each domain is divided into subdomains A and B comprising common structural motifs. The HSA gene is localized to the human chromosome 4q13.3.[3]

Physical form

30% solution in 20 mM Tris-HCl, 0.1% NaN₃, pH 6-8.

Preparation Note

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 3