P9159

Piperidine-4-sulfonic acid

Name: Piperidine-4-sulfonic acid
Brand: SIGMA
Price: 625.6 PLN

Synonym(s):

P4S

Slide 1 of 2

Select a Size

25 MG

PLN 625.60

250 MG

PLN 2,890.00

PLN 625.60

List PricePLN 736.00Save 15%

Please contact Customer Service for Availability

Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):

C₅H₁₁NO₃S

CAS Number:

72450-62-5

Molecular Weight:

165.21

NACRES:

NA.77

PubChem Substance ID:

24278165

UNSPSC Code:

12352106

MDL number:

MFCD00055097

Key Documents

View All Documentation

InChI

1S/C5H11NO3S/c7-10(8,9)5-1-3-6-4-2-5/h5-6H,1-4H2,(H,7,8,9)

SMILES string

OS(=O)(=O)C1CCNCC1

InChI key

UGBJGGRINDTHIH-UHFFFAOYSA-N

form

powder

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item	D1262	P9625	D2531
Sigma-Aldrich P9159 Piperidine-4-sulfonic acid	Sigma-Aldrich D1262 P¹,P⁴-Di(adenosine-5′) tetraphosphate ammonium salt	Sigma-Aldrich P9625 Phenazine methosulfate	Sigma-Aldrich D2531 Dextromethorphan hydrobromide monohydrate
form powder	form powder	form powder	form powder
Gene Information human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)	Gene Information human ... PLD1(5337), PLD2(5338), PLD3(23646), PLD4(122618), PLD5(200150)	Gene Information -	Gene Information human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), SIGMAR1(10280)

Biochem/physiol Actions

GABA_A receptor agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

0000379482

0000300095

0000234465

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Modulation of GABA(A) receptor channel gating by pentobarbital.

J H Steinbach et al.

The Journal of physiology, 537(Pt 3), 715-733 (2001-12-18)

1. We have studied the kinetic properties of channel gating of recombinant alpha 1 beta 2 gamma 2L GABA(A) receptors transiently expressed in human embryonic kidney 293 cells, using the cell-attached, single-channel patch-clamp technique. The receptors were activated by GABA

The role of the laterodorsal tegmental nucleus of the rat in experimental seizures.

J W Miller et al.

Neuroscience, 43(1), 41-49 (1991-01-01)

This study determined the effects of discrete microinjections of GABA agonists in the cholinergic nuclei of the pontomesencephalic tegmentum on spontaneous behavior and seizures induced by intravenous pentylenetetrazol, bicuculline or strychnine, in the rat. Injections of both the GABAA agonist

Characterization of GABAergic seizure regulation in the midline thalamus.

J W Miller et al.

Neuropharmacology, 29(7), 649-655 (1990-07-01)

This study characterized the role of GABA in the central medial intralaminar nucleus on seizures induced by pentylenetetrazol given systemically. Injections of the direct selective GABAA agonist, piperidine-4-sulfonic acid or the indirect GABAA agonists, flurazepam and pentobarbital, in this region

Entropy as the predominant driving force of binding to human recombinant alpha(x)beta(3)gamma(2) GABA(A) receptors.

G Maksay et al.

European journal of pharmacology, 411(1-2), 55-60 (2001-01-04)

In order to study the correlation of the thermodynamic driving forces of binding with the efficacies of displacing ligands, the specific binding of [3H]SR 95531 [2-(3-carboxypropyl)3-amino-6-p-methoxyphenylpyridazinium bromide], a GABA(A) receptor antagonist, was studied in cell lines stably expressing human alpha(1)beta(3)gamma(2)

The apparent voltage dependence of GABAA receptor activation and modulation is inversely related to channel open probability.

Kate K O'Toole et al.

Molecular pharmacology, 81(2), 189-197 (2011-11-02)

The GABA type A receptor (GABA(A)R) is expressed ubiquitously throughout the brain and is a target for many therapeutic agents, including general anesthetics and benzodiazepines, which enhance receptor function by increasing the open probability (P(o)) of the ion channel. It

View All Related Papers

Articles

DISCOVER Bioactive Small Molecules for Neuroscience

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service