This product is not a pharmaceutical grade item, it is intended for research use only. Currently, a pharmaceutical grade Tolfernamic acid is not offered.
T0535
Tolfenamic acid
NSAID
Synonym(s):
2 (3-Chloro-2-methylanilino)benzoic acid, 2-([3-Chloro-2-methylphenyl]amino)benzoic acid
Sign In to View Organizational & Contract Pricing.
Select a Size
5 G
PLN 404.00
About This Item
Empirical Formula (Hill Notation):
C14H12ClNO2
CAS Number:
Molecular Weight:
261.70
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
237-264-3
MDL number:
Skip To
Product Name
Tolfenamic acid, NSAID
InChI key
YEZNLOUZAIOMLT-UHFFFAOYSA-N
InChI
1S/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18)
SMILES string
Cc1c(Cl)cccc1Nc2ccccc2C(O)=O
assay
≥98% (TLC)
form
powder
solubility
ethanol: 50 mg/mL, clear, greenish-yellow
Quality Level
Looking for similar products? Visit Product Comparison Guide
1 of 4
This Item | 34073 | Y0000154 | SML3472 |
|---|---|---|---|
| assay ≥98% (TLC) | assay - | assay - | assay ≥98% (HPLC) |
| Quality Level 200 | Quality Level 100 | Quality Level - | Quality Level 100 |
| form powder | form - | form - | form powder |
| solubility ethanol: 50 mg/mL, clear, greenish-yellow | solubility - | solubility - | solubility DMSO: 2 mg/mL, clear |
Application
Tolfenamic acid has been used in Arabidopsis bud assay for activity comparison with quinazolinedione derivatives (QADD) based compounds.[1]
Biochem/physiol Actions
Non-steroidal anti-inflammatory agent. Interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Tolfenamic acid, metoclopramide, caffeine and their combinations in the treatment of migraine attacks
Tokola R A, et al.
Cephalalgia, 4(4), 253-263 (1984)
Polymer-induced heteronucleation of tolfenamic acid: structural investigation of a pentamorph
Lopez M V, et al.
Journal of the American Chemical Society, 131(13), 4554-4555 (2009)
Cyril Hamiaux et al.
The Biochemical journal, 476(12), 1843-1856 (2019-06-13)
Strigolactones (SLs) are multifunctional plant hormones regulating essential physiological processes affecting growth and development. In vascular plants, SLs are recognized by α/β hydrolase-fold proteins from the D14/DAD2 (Dwarf14/Decreased Apical Dominance 2) family in the initial step of the signaling pathway.
Vilmalí López-Mejías et al.
Journal of the American Chemical Society, 131(13), 4554-4555 (2009-04-02)
The nonsteroidal anti-inflammatory drug (NSAID) tolfenamic acid (TA), previously thought to be dimorphic, is demonstrated to have at least five polymorphs. The new forms were uncovered through the emerging screening technique of polymer-induced heteronucleation (PIHn). The presence of conformational changes
Chemical synthesis and characterization of a new quinazolinedione competitive antagonist for strigolactone receptors with an unexpected binding mode
Hamiaux C, et al.
The Biochemical Journal, 476(12), 1843-1856 (2019)
-
I am a research pharmacist looking for a source of pharmaceutical-grade tolfenamic acid. Is this powder pharmaceutical grade, and acceptable for use in humans after compounding into tablets/capsules?
1 answer-
Helpful?
-
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service