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ACLY

ATP citrate lyase

Synonimy:
ACL, ATPCL, CLATP
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(47) Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(104112) ATP citrate lyase
  • Rat(24159) ATP citrate lyase
  • chicken(395373) ATP citrate lyase
  • naked mole-rat(101700349) ATP citrate lyase
  • domestic guinea pig(100714933) ATP citrate lyase
  • dog(607852) ATP citrate lyase
  • Horse(100053195) ATP citrate lyase
  • domestic cat(100422779) ATP citrate lyase
  • cow(511135) ATP citrate lyase
  • sheep(654404) ATP citrate lyase

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Przeciwciało anty-ACLY, klon 5F8D11, clone 5F8D11, from mouse,
Reaktywność gatunkowa
human, monkey, mouse
Zastosowanie
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot

Proteins

Numer produktu
Opis
Gatunek
ATP Citrate Lyase Active human, recombinant, expressed in baculovirus, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human ACLY,
Gatunek
human
MISSION® esiRNA, targeting mouse Acly,
Gatunek
mouse