Przejdź do zawartości
Merck

GRM7

glutamate receptor, metabotropic 7

Synonimy:
GLUR7, GPRC1G, MGLU7, MGLUR7
Gatunek:
Human GRM7 (2917), Mouse Grm7 (108073), Rat Grm7 (81672), Zebrafish grm7 (564461), chicken GRM7 (416112), Horse GRM7 (100052696), domestic cat GRM7 (101090088), Domestic Rabbit GRM7 (100343810), cow GRM7 (535362), dog GRM7 (484674)
Identyfikator UniProtKB:
Q14831, Q8NFS2, Q8NFS3, Q8NFS4
Identyfikator genu:
  • Human(2917) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
  • Mouse(108073) glutamate receptor, metabotropic 7
  • Rat(81672) glutamate receptor, metabotropic 7
  • Zebrafish(564461) glutamate receptor, metabotropic 7
  • chicken(416112) glutamate receptor, metabotropic 7
  • Horse(100052696) glutamate receptor, metabotropic 7
  • domestic cat(101090088) glutamate receptor, metabotropic 7
  • Domestic Rabbit(100343810) glutamate receptor, metabotropic 7
  • cow(535362) glutamate receptor, metabotropic 7
  • dog(484674) glutamate receptor, metabotropic 7

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
P0878
O-Phospho-L-serine, ,
Gatunek
human
A155
trans-(±)-ACPD monohydrate, solid, ≥97% (NMR),
Gatunek
human
A7929
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Gatunek
rat, human
G1251
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Gatunek
rat, human
G8415
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Gatunek
rat, human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
A4910
DL-2-Amino-3-phosphonopropionic acid, ,
Gatunek
human
G1251
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Gatunek
rat, human
G8415
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Gatunek
rat, human
W328502
L-Glutamic acid, FCC,
Gatunek
rat, human
49449
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Gatunek
rat, human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4501325
Anti-MGLUR7 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
07-239
Przeciwciało anty-mGluR7, Upstate®, from rabbit,
Reaktywność gatunkowa
rat
Zastosowanie
western blot
SAB4501326
Anti-GRM7 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
western blot
SAB1403886
Monoclonal Anti-GRM7 antibody produced in mouse, clone 1H5, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
AB9213
Przeciwciało przeciwko metabotropowemu receptorowi glutaminianu 7, Chemicon®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
A7929
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Gatunek
rat, human
G1251
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Gatunek
rat, human
G8415
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Gatunek
rat, human
W328502
L-Glutamic acid, FCC,
Gatunek
rat, human
49449
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Gatunek
rat, human

esiRNA

Numer produktu
Opis
Gatunek
EMNC009781
MISSION® esiRNA, targeting mouse Ak032068,
Gatunek
mouse
EHU068401
MISSION® esiRNA, targeting human GRM7,
Gatunek
human