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Merck

SLC6A2

solute carrier family 6 (neurotransmitter transporter), member 2

Synonimy:
NAT1, NET, NET1, SLC6A5
Gatunek:
Human SLC6A2 (6530), Mouse Slc6a2 (20538), Rat Slc6a2 (83511), domestic guinea pig Slc6a2 (100723578), naked mole-rat Slc6a2 (101716834), sheep SLC6A2 (101116078), sheep SLC6A2 (443100), Domestic Rabbit SLC6A2 (100328959), dog SLC6A2 (487272), domestic cat SLC6A2 (101099605) ...Więcej
Identyfikator UniProtKB:
P23975, B2R707, Q96KH8
Identyfikator genu:
  • Human(6530) Summary: This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(20538) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Rat(83511) solute carrier family 6 (neurotransmitter transporter), member 2
  • domestic guinea pig(100723578) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • naked mole-rat(101716834) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(101116078) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(443100) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Domestic Rabbit(100328959) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • dog(487272) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(101099605) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(493768) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Horse(100061346) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • cow(282363) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • chicken(395458) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

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Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
32950
4,4′-Diaminodiphenylmethane, ≥97.0% (GC),
Gatunek
mouse, rat
N5536
Nefazodone hydrochloride, ≥98% (HPLC), solid,
Gatunek
human
1457902
Nefazodone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
PHR1841
Amoxapine, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
A-123
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB2109032
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
SAB2108224
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
HPA076311
Anti-SLC6A2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
AB5066P
Anti-Norepinephrine Transporter Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
ELISA
western blot
MAB5620
Przeciwciało przeciwko transporterowi noradrenaliny, ascites fluid, Chemicon®,
Reaktywność gatunkowa
human, monkey
Zastosowanie
immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Y0001587
Atomoxetine for impurity A identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
A-095
Atomoxetine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
D-906
Desipramine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
T7947
(R)-Tomoxetine hydrochloride, solid,
Gatunek
human
M-920
Maprotiline hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU097611
MISSION® esiRNA, targeting human SLC6A2,
Gatunek
human

Small Molecule - Substrate

Numer produktu
Opis
Gatunek
1076352
Bretylium tosylate, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
1301801
Monosiarczan guanetydyny, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
BP181
Guanethidine monosulfate, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human