1076352

Bretylium tosylate

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate
• Wzór empiryczny (zapis Hilla): C₁₈H₂₄BrNO₃S
• Numer CAS: 61-75-6
• Masa cząsteczkowa: 414.36
• NACRES: NA.24
• PubChem Substance ID: 329749129
• UNSPSC Code: 41116107
• MDL number: MFCD00038731

Właściwości

• grade: pharmaceutical primary standard
• agency: USP
• API family: bretylium
• manufacturer/tradename: USP
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• SMILES string: Cc1ccc(cc1)S([O-])(=O)=O.CC[N+](C)(C)Cc2ccccc2Br
• InChI: 1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
• InChI key: KVWNWTZZBKCOPM-UHFFFAOYSA-M
• Gene Information: human ... SLC6A2(6530)

Opis

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bretylium tosylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Bretylium Tosylate Injection
• Bretylium Tosylate in Dextrose Injection

Biochem/physiol Actions

Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade; class III antiarrhythmic agent; competitive inhibitor of acetylcholinesterase.

Class III antiarrhythmic agent; competitive inhibitor of acetylcholinesterase.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302 + H312 + H332
• Ostrzeżenia: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable