This product is tested in a kinase assay using cdk2/cyclin A, active (14-448), to phosphorylate histone H1. The Certificate of Analysis contains the kinase assay procedure.
14-155
Białko histonu H1, 20 mg
Purified bovine Histone H1 protein for use as a substrate in histone modification assays (HAT, HDAC, DNMT) and chromatin assembly studies.
Synonim(y):
Łącznik Histone H1
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Wybierz wielkość
20 MG
2080,00 zł
2080,00 zł
Przewidywany termin wysyłki02 lutego 2026Szczegóły
Informacje o tej pozycji
Kod UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.32
Przejdź do
Pomoc techniczna
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Pozwól nam pomócpochodzenie biologiczne
bovine
Poziom jakości
masa cząsteczkowa
Mw 32 kDa
producent / nazwa handlowa
Upstate®
metody
activity assay: suitable (kinase)
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
dry ice
1 of 4
Ta pozycja | 05-1324 | H1917 | 06-1358 |
|---|---|---|---|
| technique(s) activity assay: suitable (kinase) | technique(s) immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable | technique(s) - | technique(s) dot blot: suitable, western blot: suitable |
| biological source bovine | biological source mouse | biological source human | biological source rabbit |
| mol wt Mw 32 kDa | mol wt - | mol wt - | mol wt - |
| shipped in dry ice | shipped in wet ice | shipped in wet ice | shipped in wet ice |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
Opis ogólny
H1 and related linker histones are important both for maintenance of higher-order chromatin structure and for the regulation of gene expression. Nucleosomal stabilization is provided through the binding of histone H1 to the nucleosomal dyad and the linker DNA entering and exiting the core particle. Additional experimental evidence illustrates the influence of histone H1 on chromatin arrangement and compaction. The family of histone H1 proteins contains five somatic variants (H1.1, H1.2, H1.3, H1.4 and H1.5) which are expressed in nearly all cell types.
Product Source: Lysine rich fraction from calf thymus
Postać fizyczna
Sterilized through a 0.2 micron membrane filter
Uwaga dotycząca przygotowania
1 year at -20°C
Komentarz do analizy
Routinely evaluated by Kinase assay using cdk2/cyclin A, active (14-448) to phosphorylate Histone H1.
Inne uwagi
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
This product is derived from bovine source. Export of this product to certain countries may be restricted. Please contact Customer Service or your local distributor to inquire about product availability and export options.
Informacje prawne
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
nwg
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Hyo Kyun Chung et al.
The Journal of biological chemistry, 278(30), 28079-28088 (2003-04-30)
The Gadd45 family of proteins includes Gadd45alpha, MyD118/Gadd45beta, and CR6/OIG37/Gadd45gamma. These proteins play important roles in maintaining genomic stability and in regulating the cell cycle. This study reports the cloning of a novel protein called CR6-interacting factor 1 (CRIF1) which
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Islets null
Rocío Montes de Oca et al.
The Journal of biological chemistry, 280(51), 42252-42262 (2005-10-06)
Barrier to autointegration factor (BAF) is an essential conserved double-stranded DNA-binding protein in metazoans. BAF binds directly to LEM domain nuclear proteins (e.g. LAP2, Emerin, and MAN1), lamin A, homeodomain transcription factors, and human immunodeficiency virus type 1-encoded proteins. BAF
J Pan et al.
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We report here a novel role for Jun dimerization protein-2 (JDP2) as a regulator of the progression of normal cells through the cell cycle. To determine the role of JDP2 in vivo, we generated Jdp2-knockout (Jdp2KO) mice by targeting exon-1
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Hi can this be used for enzymatic assays?
1 answer-
Helpful?
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Sowohl die NCBI- als auch die Uni-Prot Nummer führen zu einer humanen Datenkarte, anstatt zu einer bovinen. Warum?
1 answer-
Thank you for notifying us about the mismatch. Please find the relevant links here:
https://www.ncbi.nlm.nih.gov/gene/617854
https://www.uniprot.org/uniprotkb/G3MWV5/entryHelpful?
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