AB5384

Anti-Nitric Oxide Synthase II Antibody

serum, Chemicon^®

• Synonim(y): NOS II, iNOS
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC, WB
• Citations: 10

Właściwości

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable, western blot: suitable
• NCBI accession no.: NM_000625.3, NM_153292.1
• UniProt accession no.: P35228
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... NOS2(4843)

Opis

General description

The inducible isoform of the enzyme nitric oxide synthase (iNOS, NOS-II) is synthesized by macrophages and many other cell types in response to proinflammatory cytokines and certain other stimuli, such as hypoxia and stress.

Immunogen

C-terminal 19 amino acid peptide from human chondrocyte nitric oxide synthase.

Application

Detect Nitric Oxide Synthase II using this Anti-Nitric Oxide Synthase II Antibody validated for use in WB, IH.

Research Category
Neuroscience

Research Sub Category
Oxidative Stress

Western blot: 1:1,000-1:2,500 (ECL).

Immunohistochemistry: 1:2,500-1:6,000 (ABC).

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Inducible nitric oxide synthase (iNOS, NOS-II). No cross-reaction with nNOS and eNOS by immunohistochemistry. AB5384 reacts with human glia and certain neurons in Alzheimer′s disease by immunohistochemistry.

Physical form

Rabbit serum. Liquid containing 0.05% sodium azide.

Preparation Note

Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids
• Co się dzieje?: WGK 1