MAB342A4

Anti-Galactocerebroside Antibody, clone mGalC, Alexa Fluor^™488 Conjugate

clone mGalC, from mouse, ALEXA FLUOR^™ 488

• Synonim(y): Galactoceramide, Galactocerebroside, Galactosylceramide, GalC
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: ALEXA FLUOR^™ 488
• Clone: mGalC, monoclonal
• Application: ICC
• Citations: 3

Właściwości

• biological source: mouse
• Quality Segment: 100
• conjugate: ALEXA FLUOR^™ 488
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: mGalC, monoclonal
• species reactivity: rabbit, rat
• species reactivity (predicted by homology): human, bovine (immunogen homology), chicken, mouse
• technique(s): immunocytochemistry: suitable
• isotype: IgG3
• shipped in: wet ice
• target post-translational modification: unmodified

Opis

General description

Galactocerebroside (GalC) is a major galactosphingolipid of myelin which plays a role in myelination. GalC is a very useful, specific marker for oligodendroglial lineage.

Application

Detect Galactocerebroside using this Anti-Galactocerebroside Antibody, clone mGalC, Alexa Fluor^™488 Conjugate validated for use in ICC.

Biochem/physiol Actions

This antibody recognizes Galactocerebroside (GalC), sulfatide, psychosine and other galactolipids. Cross-reacts with the sulfatide ester of GalC, but to a 16-fold to a lesser extent. No cross-reactivity with sphingosine, ceramide, mixed ganglioside or glucocerebroside. Binds specifically with oligodendrocytes and Schwann cells.

Physical form

Purified mouse monoclonal IgG3 conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Analysis Note

Control
Rat oligodendrocyte cells

Evaluated by Immunocytochemistry in rat oligodendrocyte cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Galactocerebroside in rat oligodendrocyte cells. Performed without Triton.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

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