34089

Fosfomycin sodium

VETRANAL^®, analytical standard

• Synonim(y): Phosphomycin disodium salt, (−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, Fosfomycin, Phosphonomycin
• Wzór empiryczny (zapis Hilla): C₃H₅Na₂O₄P
• Numer CAS: 26016-99-9
• Masa cząsteczkowa: 182.02
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329754806
• EC Number: 247-409-2
• Beilstein/REAXYS Number: 4604425
• MDL number: MFCD22741288
• eCl@ss: 25140904

Właściwości

• grade: analytical standard
• Quality Segment: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: [Na+].[Na+].C[C@@H]1O[C@@H]1P([O-])([O-])=O
• InChI: 1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1
• InChI key: QZIQJIKUVJMTDG-JSTPYPERSA-L

Opis

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)